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The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members.
Gene Name: | tripartite motif containing 6 |
Family/Subfamily: | Tripartite Motif |
Synonyms: | TRIM6, RING finger protein 89, RNF89, Tripartite motif containing 6, Tripartite motif-containing 6 |
Target Sequences: | AF220030 AAG53484.1 Q9C030 |
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