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TRIM13

tripartite motif containing 13

E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation. Regulates ER stress-induced autophagy, and may act as a tumor suppressor.

Gene Name: tripartite motif containing 13
Family/Subfamily: Tripartite Motif
Synonyms: TRIM13, DLEU5, CLL-associated RING finger, LEU5, Leukemia-associated protein 5, RING finger protein 77, Tripartite motif protein 13, Putative tumor suppressor RFP2, RFP2, CAR, Ret finger protein 2, RNF77, Tripartite motif containing 13, Tripartite motif-containing 13
Target Sequences: NM_005798 NP_005789.2 O60858

☰ Filters
Products
Proteins (12)
Over-Expression Lysate (9)
Recombinant (3)
TRIM13 (12)
No (12)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (10)
Human (8)
293T Cells (5)
HEK 293 Cells (5)
Wheat Germ Extract (2)
Purified (1)
TRIM13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
47.2 kDa
100 µg/$494
TRIM13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
46.8 kDa
100 µg/$494
TRIM13 Protein - 12.5% SDS-PAGE of human RFP2 stained with Coomassie Blue
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Wheat Germ Extract
GST
73.7 kDa
10 µg/$479; 25 µg/$670
TRIM13 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TRIM13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
46.8 kDa
100 µg/$494
TRIM13 Protein - Purified recombinant protein TRIM13 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
46.8 kDa
20 µg/$1,107
TRIM13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
47.2 kDa
20 µg/$150
TRIM13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.8 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
46.8 kDa
20 µg/$150
TRIM13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.8 kDa
20 µg/$150
TRIM13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.8 kDa
20 µg/$150
TRIM13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
46.8 kDa
100 µg/$494
Viewing 1-12 of 12 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).