TRAIL-R4 / DCR2

tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

TRAIL-R4 / DCR2 (6)

Publications

No (6)

Tag

Fc, C-terminus (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (2)

Species

Human (5)

Source

293T Cells (1)

HEK 293 Cells (1)

Human (1)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (3)

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Human TRAIL-R4 / DCR2 Protein (Recombinant GST, N-terminus) (aa56-145) - LS-G60865

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TRAIL-R4 / DCR2 Protein (Recombinant His) (Met1-His211) - LS-G97960

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

18.4 kDa

Price:

100 µg/$502

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Human TRAIL-R4 / DCR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80339

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.7 kDa

Price:

20 µg/$150

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TRAIL-R4 / DCR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100142

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.7 kDa

Price:

100 µg/$494

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Human TRAIL-R4 / DCR2 Protein (Recombinant Fc, C-terminus) (Ala56-His211) - LS-G138751

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

43.4 kDa

Price:

10 µg/$262; 50 µg/$317

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Human TRAIL-R4 / DCR2 Protein (Recombinant) (Ala56-His211) - LS-G55729

Source:

Human

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

43.4kD

Price:

10 µg/$262; 50 µg/$321; 500 µg/$802; 1 mg/$1,113

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