TRAIL-R4 / DCR2

tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis.

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Products

ELISA Kits (4)

Type

Custom (1)

Sandwich (3)

Target

TRAIL-R4 / DCR2 (4)

Reactivity

Human (4)

Format

96-Well Microplate (1)

96-Well Strip Plate (2)

Publications

No (4)

Sample Type

Cell Culture Supernatants (2)

Citrate Plasma (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (2)

Serum (3)

Tissue Homogenates (1)

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Human TRAIL-R4 / DCR2 (Custom ELISA) ELISA Kit - LS-F20378

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$685

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Human TRAIL-R4 / DCR2 (Sandwich ELISA) ELISA Kit - LS-F52762

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$870

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Human TRAIL-R4 / DCR2 (Sandwich ELISA) ELISA Kit - LS-F57186

Type:

Sandwich

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Sample Types:

Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$795

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Human TRAIL-R4 / DCR2 (Sandwich ELISA) ELISA Kit - LS-F202

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

5.487 - 1333 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

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