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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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TRAF7
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.
| Gene Name: | TNF receptor-associated factor 7, E3 ubiquitin protein ligase |
| Synonyms: | TRAF7, RFWD1, RING finger protein 119, RNF119 |
| Target Sequences: | NM_032271 NP_115647.2 Q6Q0C0 |
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