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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TRAF3IP2 / ACT1

TRAF3 interacting protein 2

Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB associates with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. IkB is phosphorylated by IkB kinase (IKK) complex that contains IKKa, IKKb, and IKKg. A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-kB activator 1). CIKS directly interacts with IKKg. CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK). These results indicate that CIKS/Act1 is involved in the inflammation and stress responses. CIKS/Act1 is ubiquitously expressed in human tissues.

Gene Name: TRAF3 interacting protein 2
Synonyms: TRAF3IP2, C6orf2, C6orf4, C6orf5, CIKS, DKFZP586G0522, Connection to IKK and SAPK/JNK, ACT1, Adapter protein CIKS, NFkB-activating protein ACT1, PSORS13, TRAF3-interacting protein 2, C6orf6, TRAF3 interacting protein 2
Target Sequences: NM_147200 NP_671733.1 O43734

Filtered by: None
Target
TRAF3IP2 / ACT1 (45)
Reactivity
Human (45)
Mouse (5)
Rat (5)
Monkey (1)
Pig (4)
Application
IHC (9)
IHC-P (4)
WB (44)
ELISA (13)
IF (3)
Peptide-ELISA (1)
Host
rabbit (43)
mouse (1)
goat (1)
Isotype
IgG (35)
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (44)
Clone
4A3 (1)
Format
AP Conjugated (4)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (20)
Epitope
aa463-492 (8)
N-Terminus (6)
aa1-300 (1)
aa159-170 (1)
aa2-15 (1)
aa554-568 (1)
Publications
No (45)
Showing 1-25 of 45 results

IHC-plus™ TRAF3IP2 / ACT1 Antibody (clone 4A3) LS-B5448
Mouse Monoclonal [clone 4A3] (IgG2a,k) to Human TRAF3IP2 / ACT1
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-TRAF3IP2 / ACT1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of monoclonal antibody to TRAF3IP2 on HeLa cell. [antibody concentration 10 ug/ml]

TRAF3IP2 / ACT1 Antibody LS-C616
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Mouse, Human, Monkey
WB
Unconjugated
100µg 200µl 0.5mg/ml  $335.00
Western blot of CIKS using antibody on 15 ugs of mouse kidney cell lysate.

IHC-plus™ TRAF3IP2 / ACT1 Antibody LS-B1429
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $545.00
Anti-TRAF3IP2 / ACT1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 1 ug/ml.
Immunofluorescence of CIKS in human lung tissue with CIKS antibody at 20 ug/ml.

TRAF3IP2 / ACT1 Antibody LS-C482707
Rabbit Polyclonal to Human TRAF3IP2 / ACT1
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Immunohistochemical analysis of ACT1 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of ACT1 expression in MCF7 (A); mouse kidney (B) whole cell lysates.

TRAF3IP2 / ACT1 Antibody LS-C334941
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Mouse, Human
IHC, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded Human liver injury tissue.
Western blot analysis of extracts of various cell lines.

TRAF3IP2 / ACT1 Antibody LS-C408
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, IF, IHC, WB
Unconjugated
0.1mg  $365.00
Immunohistochemistry of CIKS in human lung tissue with CIKS antibody at 5 ug/ml.
Immunofluorescence of CIKS in Human Lung cells with CIKS antibody at 20 ug/ml.

TRAF3IP2 / ACT1 Antibody (N-Terminus) LS-C135292
Rabbit Polyclonal to Human TRAF3IP2 / ACT1
Rat, Pig, Human
WB
Unconjugated
100µl 0.5mg/ml  $365.00
TRAF3IP2 / ACT1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

TRAF3IP2 / ACT1 Antibody LS-C401098
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, IHC, WB
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human colon cancer using TRAF3IP2 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of paraffin-embedded Human liver cancer using TRAF3IP2 Polyclonal Antibody at dilution of 1:30.

TRAF3IP2 / ACT1 Antibody LS-C404360
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, IHC, WB
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human colon cancer using TRAF3IP2 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of paraffin-embedded Human liver cancer using TRAF3IP2 Polyclonal Antibody at dilution of 1:25.

TRAF3IP2 / ACT1 Antibody (aa1-300) LS-C376919
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, IHC, IHC-P
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human colon cancer using antibody at 1:100 dilution.

TRAF3IP2 / ACT1 Antibody LS-C771355
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Mouse, Rat, Human
IHC, WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

TRAF3IP2 / ACT1 Antibody (aa463-492) LS-C325909
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, WB
Unconjugated
200µl  $590.00

TRAF3IP2 / ACT1 Antibody (aa463-492, Biotin) LS-C224425
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

TRAF3IP2 / ACT1 Antibody (aa463-492, FITC) LS-C224426
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, WB
FITC Conjugated
200µl  $740.00

TRAF3IP2 / ACT1 Antibody (aa463-492, Azide-free, HRP) LS-C224427
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl  $740.00

TRAF3IP2 / ACT1 Antibody (aa463-492, PE) LS-C224432
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, WB
PE Conjugated
200µl  $740.00

TRAF3IP2 / ACT1 Antibody (aa463-492, AP) LS-C224423
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, WB
AP Conjugated
200µl  $740.00

TRAF3IP2 / ACT1 Antibody (aa463-492, APC) LS-C224424
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
ELISA, WB
APC Conjugated
200µl  $740.00

TRAF3IP2 / ACT1 Antibody (aa159-170) LS-C186619
Goat Polyclonal to Human TRAF3IP2 / ACT1
Human
Peptide-ELISA, WB
Unconjugated
100µg 0.5mg/ml  $405.00
TRAF3IP2 antibody (2 ug/ml) staining of MCF7 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

TRAF3IP2 / ACT1 Antibody LS-C746662
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
WB
Unconjugated
50µg  $355.00

TRAF3IP2 / ACT1 Antibody (N-Terminus) LS-C83745
Rabbit Polyclonal to Human TRAF3IP2 / ACT1
Mouse, Human
WB
Unconjugated
100µg 1mg/ml  $335.00

TRAF3IP2 / ACT1 Antibody (aa554-568) LS-C153103
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
WB
Unconjugated
100µg  $435.00

TRAF3IP2 / ACT1 Antibody (aa2-15) LS-C153104
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
WB
Unconjugated
100µg  $435.00

TRAF3IP2 / ACT1 Antibody LS-C309919
Rabbit Polyclonal (IgG) to Human TRAF3IP2 / ACT1
Human
WB
Unconjugated
100µg  $605.00

TRAF3IP2 / ACT1 Antibody (aa463-492) LS-C157253
Rabbit Polyclonal to Human TRAF3IP2 / ACT1
Human
WB
Unconjugated
400µl  $325.00
TRAF3IP2 Antibody western blot of HeLa cell line lysates (35 ug/lane). The TRAF3IP2 antibody detected the TRAF3IP2 protein (arrow).
Showing 1-25 of 45 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).