TRAF3

TNF receptor-associated factor 3

Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote 'Lys-63'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

TRAF3 (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human TRAF3 Protein (Recombinant GST, N-terminus) (aa298-410) - LS-G60416

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TRAF3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65209

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.3 kDa

Price:

20 µg/$1,107

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TRAF3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117436

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.3 kDa

Price:

100 µg/$494

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Human TRAF3 Protein (Recombinant GST) (Full Length) - LS-G30770

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

90.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TRAF3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75086

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.3 kDa

Price:

20 µg/$150

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Human TRAF3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75087

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.3 kDa

Price:

20 µg/$150

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TRAF3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102322

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.3 kDa

Price:

100 µg/$494

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