TPSD1 / Tryptase Delta 1

Tryptase Delta 1

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

TPSD1 / Tryptase Delta 1 (4)

Publications

No (4)

Tag

GST (1)

His-S (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human TPSD1 / Tryptase Delta 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88720

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.4 kDa

Price:

20 µg/$150

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TPSD1 / Tryptase Delta 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114558

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.4 kDa

Price:

100 µg/$494

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Human TPSD1 / Tryptase Delta 1 Protein (Recombinant GST) (Full Length) - LS-G32841

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

53 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TPSD1 / Tryptase Delta 1 Protein (Recombinant His-S) (aa99-191) - LS-G15359

Source:

E. coli

Tag:

His-S

Molecular Weight:

16.2 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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