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TPRKB

TP53RK binding protein

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.

Gene Name: TP53RK binding protein
Synonyms: TPRKB, CGI-121, TP53RK binding protein, PRPK-binding protein, TP53RK-binding protein
Target Sequences: NM_016058 NP_057142.1 Q9Y3C4

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
TPRKB (6)
No (6)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
TPRKB Protein - 12.5% SDS-PAGE of human CGI-121 stained with Coomassie Blue
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Wheat Germ Extract
GST
46.1 kDa
10 µg/$479; 25 µg/$670
TPRKB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
19.5 kDa
100 µg/$494
TPRKB Protein - Purified recombinant protein TPRKB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
19.5 kDa
20 µg/$1,107
TPRKB Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TPRKB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
19.5 kDa
20 µg/$150
TPRKB Protein
Select
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).