LSBio
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA and Assay Kits
  • All Kits
  • Assay Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Biochemicals
  • All Biochemicals

  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure ShareFile Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login ▾
Wish List
View Cart

Unfortunately, the antibody (ID:91861) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



TPR

translocated promoter region, nuclear basket protein

Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs, plays a role in the establishment of nuclear-peripheral chromatin compartmentalization in interphase, and in the mitotic spindle checkpoint signaling during mitosis. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with NUP153, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Negatively regulates both the association of CTE-containing mRNA with large polyribosomes and translation initiation. Does not play any role in Rev response element (RRE)-mediated export of unspliced mRNAs. Implicated in nuclear export of mRNAs transcribed from heat shock gene promoters; associates both with chromatin in the HSP70 promoter and with mRNAs transcribed from this promoter under stress-induced conditions. Modulates the nucleocytoplasmic transport of activated MAPK1/ERK2 and huntingtin/HTT and may serve as a docking site for the XPO1/CRM1-mediated nuclear export complex. According to some authors, plays a limited role in the regulation of nuclear protein export (PubMed:22253824 and PubMed:11952838). Plays also a role as a structural and functional element of the perinuclear chromatin distribution; involved in the formation and/or maintenance of NPC-associated perinuclear heterochromatin exclusion zones (HEZs). Finally, acts as a spatial regulator of the spindle-assembly checkpoint (SAC) response ensuring a timely and effective recruitment of spindle checkpoint proteins like MAD1L1 and MAD2L1 to unattached kinetochore during the metaphase-anaphase transition before chromosome congression. Its N-terminus is involved in activation of oncogenic kinases.

Gene Name: translocated promoter region, nuclear basket protein
Synonyms: TPR, Translocated promoter region, Tumor potentiating region, Nucleoprotein TPR, Tpr-Met
Target Sequences: NM_003292 NP_003283.2 P12270

Loading ...

Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
TPR Rabbit IgG Polyclonal Unconjugated Human, Monkey, Mouse, Bovine, Dog, Pig, Rabbit IHC-P, ICC, IF C-Terminus
1
TPR Rabbit IgG Polyclonal Unconjugated Human, Monkey, Mouse, Bovine, Dog, Pig, Rabbit IHC-P, ICC, IF C-Terminus No Primary
Anti-TPR Antibody (C-Terminus) IHC-plus™ LS-B14268
Immunohistochemistry - Paraffin Image
Immunocytochemistry Image
Rabbit Polyclonal (IgG) to Human TPR
Human, Monkey, Mouse, Bovine, Dog, Pig, Rabbit
IHC - Paraffin, ICC, Immunofluorescence
Unconjugated
TPR Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat, Dog, Horse, Rabbit, Chicken IHC-P, WB, IP aa1650-1700
1
TPR Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat, Dog, Horse, Rabbit, Chicken IHC-P, WB, IP aa1650-1700 No Primary
Anti-TPR Antibody (aa1650-1700) IHC-plus™ LS-B13990
Immunohistochemistry - Paraffin Image
Rabbit Polyclonal (IgG) to Human TPR
Human, Mouse, Rat, Dog, Horse, Rabbit, Chicken
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
TPR Rabbit Polyclonal Unconjugated,HRP Conjugated,Biotin Conjugated,FITC Conjugated Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit WB,WB,WB,WB aa2276-2325
4
TPR Rabbit Polyclonal Unconjugated Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit WB aa2276-2325 No Primary Available
Anti-TPR Antibody (aa2276-2325) LS-C135922
Western blot Image
Rabbit Polyclonal to Human TPR
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Western blot
Unconjugated
TPR Rabbit Polyclonal HRP Conjugated Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit WB aa2276-2325 No Primary
Anti-TPR Antibody (aa2276-2325, HRP) LS-C468265
Western blot Image
Rabbit Polyclonal to Human TPR
Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Western blot
HRP Conjugated
TPR Rabbit Polyclonal Biotin Conjugated Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit WB aa2276-2325 No Primary
Anti-TPR Antibody (aa2276-2325, Biotin) LS-C468263
Western blot Image
Rabbit Polyclonal to Human TPR
Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Western blot
Biotin Conjugated
TPR Rabbit Polyclonal FITC Conjugated Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit WB aa2276-2325 No Primary
Anti-TPR Antibody (aa2276-2325, FITC) LS-C468264
Western blot Image
Rabbit Polyclonal to Human TPR
Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Western blot
FITC Conjugated
TPR Rabbit IgG Polyclonal Unconjugated Human, Bovine, Dog, Pig, Rabbit IHC-P, ICC, IF, WB, IP C-Terminus
1
TPR Rabbit IgG Polyclonal Unconjugated Human, Bovine, Dog, Pig, Rabbit IHC-P, ICC, IF, WB, IP C-Terminus No Primary
Anti-TPR Antibody (C-Terminus) LS-C287677
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human TPR
Human, Bovine, Dog, Pig, Rabbit
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
TPR Mouse IgG1,k Monoclonal 1A8 Unconjugated Human IHC-P, WB, ELISA
1
TPR Mouse IgG1,k Monoclonal 1A8 Unconjugated Human IHC-P, WB, ELISA No Primary
Anti-TPR Antibody (clone 1A8) LS-C133494
Immunohistochemistry Image
Enzyme-Linked Immunosorbent Assay Image
Mouse Monoclonal [clone 1A8] (IgG1,k) to Human TPR
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
TPR Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, ELISA
1
TPR Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, ELISA No Primary
Anti-TPR Antibody LS-C406630
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human TPR
Human, Mouse, Rat
IHC, ELISA
Unconjugated
TPR Rabbit Polyclonal Unconjugated Human IHC, WB C-Terminus
1
TPR Rabbit Polyclonal Unconjugated Human IHC, WB C-Terminus No Primary
Anti-TPR Antibody (C-Terminus) LS-C145072
Rabbit Polyclonal to Human TPR
Human
IHC, Western blot
Unconjugated
TPR Rabbit Polyclonal Unconjugated Human WB, ELISA aa2026-2060
1
TPR Rabbit Polyclonal Unconjugated Human WB, ELISA aa2026-2060 No Primary
Anti-TPR Antibody (aa2026-2060) LS-C392644
Western blot Image
Rabbit Polyclonal to Human TPR
Human
Western blot, ELISA
Unconjugated
TPR Rabbit IgG Polyclonal Unconjugated Human WB, IP aa600-650
1
TPR Rabbit IgG Polyclonal Unconjugated Human WB, IP aa600-650 No Primary
Anti-TPR Antibody (aa600-650) LS-C286025
Rabbit Polyclonal (IgG) to Human TPR
Human
Western blot, Immunoprecipitation
Unconjugated
TPR Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat, Bovine, Dog, Guinea pig, Pig, Rabbit WB, IP aa2275-2325
1
TPR Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat, Bovine, Dog, Guinea pig, Pig, Rabbit WB, IP aa2275-2325 No Primary
Anti-TPR Antibody (aa2275-2325) LS-C287678
Rabbit Polyclonal (IgG) to Human TPR
Human, Mouse, Rat, Bovine, Dog, Guinea pig, Pig, Rabbit
Western blot, Immunoprecipitation
Unconjugated
TPR Rabbit Polyclonal Unconjugated Human WB
1
TPR Rabbit Polyclonal Unconjugated Human WB No Primary
Anti-TPR Antibody LS-C48703
Rabbit Polyclonal to Human TPR
Human
Western blot
Unconjugated
TPR Rabbit Polyclonal Unconjugated,HRP Conjugated,Biotin Conjugated,FITC Conjugated Human, Monkey, Bovine, Dog, Guinea pig, Horse, Rabbit, Chicken WB,WB,WB,WB aa2034-2083
4
TPR Rabbit Polyclonal Unconjugated Human, Monkey, Bovine, Dog, Guinea pig, Horse, Rabbit, Chicken WB aa2034-2083 No Primary Available
Anti-TPR Antibody (aa2034-2083) LS-C135923
Western blot Image
Rabbit Polyclonal to Human TPR
Human, Monkey, Bovine, Dog, Guinea pig, Horse, Rabbit, Chicken
Western blot
Unconjugated
TPR Rabbit Polyclonal HRP Conjugated Human, Chimpanzee, Gibbon, Monkey, Bovine, Dog, Guinea pig, Horse, Rabbit, Chicken WB aa2034-2083 No Primary
Anti-TPR Antibody (aa2034-2083, HRP) LS-C468268
Western blot Image
Rabbit Polyclonal to Human TPR
Human, Chimpanzee, Gibbon, Monkey, Bovine, Dog, Guinea pig, Horse, Rabbit, Chicken
Western blot
HRP Conjugated
TPR Rabbit Polyclonal Biotin Conjugated Human, Chimpanzee, Gibbon, Monkey, Bovine, Dog, Guinea pig, Horse, Rabbit, Chicken WB aa2034-2083 No Primary
Anti-TPR Antibody (aa2034-2083, Biotin) LS-C468266
Western blot Image
Rabbit Polyclonal to Human TPR
Human, Chimpanzee, Gibbon, Monkey, Bovine, Dog, Guinea pig, Horse, Rabbit, Chicken
Western blot
Biotin Conjugated
TPR Rabbit Polyclonal FITC Conjugated Human, Chimpanzee, Gibbon, Monkey, Bovine, Dog, Guinea pig, Horse, Rabbit, Chicken WB aa2034-2083 No Primary
Anti-TPR Antibody (aa2034-2083, FITC) LS-C468267
Western blot Image
Rabbit Polyclonal to Human TPR
Human, Chimpanzee, Gibbon, Monkey, Bovine, Dog, Guinea pig, Horse, Rabbit, Chicken
Western blot
FITC Conjugated
Target Corresponding Antibodies
TPR
1
TPR Antibody Blocking Peptide - LS-E22336
LS-E22336
TPR
LS-C135922
TPR
1
TPR Antibody Blocking Peptide - LS-E22337
LS-E22337
TPR
LS-C135923

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2017 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number