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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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TPMT

thiopurine S-methyltransferase

TPMT is the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

Gene Name: thiopurine S-methyltransferase
Synonyms: TPMT, Thiopurine S-methyltransferase, Thiopurine methyltransferase
Target Sequences: NM_000367 NP_000358.1 P51580

Viewing 1-25 of 42 items
TPMT Antibody - Anti-TPMT antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human TPMT
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   $425.00
TPMT Antibody - Anti-TPMT antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human TPMT
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50µg   $285.00; 100µg   $385.00
TPMT Antibody - Anti-TPMT antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human TPMT
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
TPMT Antibody - Anti-TPMT antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human TPMT
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50µg   $285.00; 100µg   $385.00
TPMT Antibody - Immunoperoxidase of monoclonal antibody to TPMT on formalin-fixed paraffin-embedded human spleen. [antibody concentration 1 ug/ml]
Select
Mouse Monoclonal [clone 1B5] (IgG1,k) to Human TPMT
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100µg   $365.00
TPMT Antibody - IHC of paraffin-embedded breast tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI2A2] (IgG1) to Human TPMT
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   0.73mg/ml   $345.00
TPMT Antibody - IHC of paraffin-embedded breast tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI2A2] (IgG1) to Human TPMT
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
TPMT Antibody - IHC of paraffin-embedded liver tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI4C1] (IgG1) to Human TPMT
Dog, Human
Flo, IHC, IHC-P, WB
Unconjugated
100µl   0.88mg/ml   $345.00
TPMT Antibody - IHC of paraffin-embedded liver tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI4C1] (IgG1) to Human TPMT
Dog, Human
Flo, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
TPMT Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human TPMT
ELISA, IHC, IHC-P, WB
Unconjugated
40µg   80µl   0.5mg/ml   $425.00
TPMT Antibody - IHC of paraffin-embedded Kidney tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI5B4] (IgG1) to Human TPMT
Human
IHC, IHC-P, WB
Unconjugated
100µl   0.6mg/ml   $345.00
TPMT Antibody - IHC of paraffin-embedded Kidney tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI5B4] (IgG1) to Human TPMT
Human
IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
TPMT Antibody - Immunofluorescence analysis of U2OS cells using TPMT antibody. Blue: DAPI for nuclear staining.
Select
Rabbit Polyclonal (IgG) to Human TPMT
Mouse, Human
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
TPMT Antibody - IHC of paraffin-embedded colon tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI4B1] (IgG1) to Human TPMT
Human
IHC, IHC-P, WB
Unconjugated
100µl   0.89mg/ml   $345.00
TPMT Antibody - IHC of paraffin-embedded colon tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI4B1] (IgG1) to Human TPMT
Human
IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
TPMT Antibody - Immunofluorescent analysis of TPMT staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Select
Rabbit Polyclonal to Human TPMT
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50µl   1mg/ml   $255.00; 100µl   1mg/ml   $295.00; 200µl   1mg/ml   $375.00
TPMT Antibody
Select
Rabbit Polyclonal (IgG) to Human TPMT
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal (IgG) to Human TPMT
Mouse, Human
IF, WB
Unconjugated
50µl   $235.00; 100µl   $295.00; 200µl   $385.00
Select
Rabbit Polyclonal (IgG) to Human TPMT
Mouse, Human
IF, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
TPMT Antibody - Western blot of TPMT pAb in extracts from K562 cells and mouse liver, kidney tissues.
Select
Rabbit Polyclonal to Human TPMT
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl   $385.00
TPMT Antibody - Western Blot: The cell lysates (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human TPMT antibody (1:1,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Select
Mouse Monoclonal [clone AT2E7] (IgG1,k) to Human TPMT
Human
ELISA, WB
Unconjugated
50µl   1mg/ml   $315.00; 100µl   1mg/ml   $345.00
Select
Rabbit Polyclonal (IgG) to Human TPMT
Human
ELISA, WB
Unconjugated
100µg   $455.00
Select
Rabbit Polyclonal (IgG) to Human TPMT
Human
ELISA, WB
Unconjugated
40µg   $405.00
Select
Rabbit Polyclonal (IgG) to Human TPMT
Human
ELISA, WB
Unconjugated
40µg   $405.00
TPMT Antibody - Western blot of recombinant human TPMT protein using 1 ug/ml Rabbit Anti-TPMT Polyclonal Antibody. The signal was developed with IRDye 800 Conjugated Goat Anti-Rabbit IgG.
Select
Rabbit Polyclonal (IgG) to Human TPMT
ELISA, WB
Unconjugated
40µg   80µl   0.5mg/ml   $245.00

Viewing 1-25 of 42 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).