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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TPH1 / Tryptophan Hydroxylase

tryptophan hydroxylase 1

TPH1 / TPH encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

Gene Name: tryptophan hydroxylase 1
Family/Subfamily: Monooxygenase
Synonyms: TPH1, L-tryptophan hydroxylase, TRPH, Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, TPRH, Tryptophan hydroxylase 1, TPH
Target Sequences: NM_004179 NP_004170.1 P17752

Publications (1)

1
Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer. Hallett RM, Girgis-Gabardo A, Gwynne WD, Giacomelli AO, Bisson JN, Jensen JE, Dvorkin-Gheva A, Hassell JA. Oncotarget. 2016 7:53137-53152. (WB; Human) [Full Text Article] [PubMed:27447971] [PMC:PMC5288174] Related Antibodies: LS-C117936.

Viewing 1-25 of 55 items
TPH1 / Tryptophan Hydroxylase Antibody - Anti-TPH1 / TPH antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Neuroscience
Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
TPH1 / Tryptophan Hydroxylase Antibody - Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Neuroscience
Sheep Polyclonal to Rabbit TPH1 / Tryptophan Hydroxylase
Rabbit, Rat, Mammal, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
50µl   $425.00
TPH1 / Tryptophan Hydroxylase Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl   $425.00
TPH1 / Tryptophan Hydroxylase Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Tryptophan Hydroxylase Antibody. The picture on the right is blocked with the synthesized peptide.
Select
Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
TPH1 / Tryptophan Hydroxylase Antibody - Immunohistochemical analysis of TPH1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Rabbit Polyclonal to Human TPH1 / Tryptophan Hydroxylase
Chicken, Rabbit, Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $275.00
TPH1 / Tryptophan Hydroxylase Antibody - Immunohistochemical analysis of TPH1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Rabbit Polyclonal to Human TPH1 / Tryptophan Hydroxylase
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $275.00
TPH1 / Tryptophan Hydroxylase Antibody - Western blot of TPH1 antibody
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Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
TPH1 / Tryptophan Hydroxylase Antibody - Western blot of TPH1 antibody
Select
Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
TPH1 / Tryptophan Hydroxylase Antibody - Immunofluorescent analysis of U251 cells using TPH1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Human
ELISA, IF, WB
Unconjugated
50µg   $285.00; 100µg   5mg/ml   $385.00
Select
Rabbit Polyclonal to Human TPH1 / Tryptophan Hydroxylase
Human
ICC, IHC, WB
Unconjugated
100µl   $445.00
TPH1 / Tryptophan Hydroxylase Antibody - Western blot of Phospho-TPH1 (S58) antibody
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Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
TPH1 / Tryptophan Hydroxylase Antibody - 1:100 staining mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
TPH1 / Tryptophan Hydroxylase Antibody - Formalin-fixed and paraffin-embedded human brain tissue with TPH1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Rabbit Polyclonal to Human TPH1 / Tryptophan Hydroxylase
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Select
Sheep Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Human
IHC-Fr, WB
Unconjugated
0.1ml   $560.00
TPH1 / Tryptophan Hydroxylase Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using Tryptophan Hydroxylase (Ab-58) antibody.
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Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $305.00
TPH1 / Tryptophan Hydroxylase Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Tryptophan Hydroxylase (Ab-260) antibody.
Select
Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $305.00
TPH1 / Tryptophan Hydroxylase Antibody - IHC of TPH1 (K54) pAb in paraffin-embedded human brain tissue.
Select
Rabbit Polyclonal to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $345.00
TPH1 / Tryptophan Hydroxylase Antibody - IHC of TPH1 (V256) pAb in paraffin-embedded human lung carcinoma tissue.
Select
Rabbit Polyclonal to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $345.00
TPH1 / Tryptophan Hydroxylase Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using Tryptophan Hydroxylase (Phospho-Ser260) Antibody. The picture on the right is blocked with the phospho peptide.
Select
Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
TPH1 / Tryptophan Hydroxylase Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using Tryptophan Hydroxylase (Phospho-Ser58) Antibody. The picture on the right is blocked with the phospho peptide.
Select
Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rabbit Polyclonal to Human TPH1 / Tryptophan Hydroxylase
Human
ICC, IHC, WB
Unconjugated
100µl   $445.00
Select
Rabbit Polyclonal to Human TPH1 / Tryptophan Hydroxylase
Human
ICC, IHC, WB
Unconjugated
100µl   $445.00
Select
Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
TPH1 / Tryptophan Hydroxylase Antibody - Western blot analysis of extracts from 293 cells, treated with paclitaxel (1uM, 24hours), using Tryptophan Hydroxylase (Phospho-Ser58) antibody.
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Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg   $305.00
TPH1 / Tryptophan Hydroxylase Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Tryptophan Hydroxylase (Phospho-Ser260) antibody.
Select
Rabbit Polyclonal (IgG) to Human TPH1 / Tryptophan Hydroxylase
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg   $305.00

Viewing 1-25 of 55 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).