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TP53I3 / PIG3

tumor protein p53 inducible protein 3

TP53I3 / PIG3 is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: tumor protein p53 inducible protein 3
Synonyms: TP53I3, PIG3, Quinone oxidoreductase homolog, p53-induced gene 3 protein, Quinone oxidoreductase PIG3
Target Sequences: NM_004881 NP_004872.2 Q53FA7

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Products
Antibodies (34)
Primary (34)
TP53I3 / PIG3 (34)
Human (34)
Mouse (2)
Rat (1)
Chimpanzee (3)
Gibbon (3)
Monkey (3)
Orangutan (3)
IHC (7)
IHC-P (4)
WB (31)
ELISA (13)
ICC (1)
IF (2)
IP (1)
Peptide-ELISA (2)
rabbit (28)
mouse (6)
IgG (13)
IgG1 (4)
IgG2a,k (1)
monoclonal mc (6)
polyclonal pc (28)
AT1C9 (1)
OTI3B11 (2)
OTI3E3 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
Carrier-free (2)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (23)
aa174-203 (7)
aa163-212 (4)
aa189-238 (4)
210-290 aa, C-terminal (1)
C-Terminus (1)
Leu265 (1)
aa1-332 (1)
aa163-332 (1)
aa241-290 (1)
No (34)
TP53I3 / PIG3 Antibody - IHC of paraffin-embedded H441 xenograft using PIG3 antibody at 1:500 dilution.
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal (aa1-332) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
TP53I3 / PIG3 Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TP53I3 / PIG3 Antibody - IHC of paraffin-embedded Human breast tissue using anti-TP53I3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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TP53I3 / PIG3 Mouse anti-Human Monoclonal (OTI3B11) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
TP53I3 / PIG3 Antibody - IHC of paraffin-embedded Human breast tissue using anti-TP53I3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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TP53I3 / PIG3 Mouse anti-Human Monoclonal (Carrier-free) (OTI3B11) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TP53I3 / PIG3 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal (aa163-332) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$351
TP53I3 / PIG3 Antibody - Western blot of PIG3 antibody
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal (210-290 aa, C-terminal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TP53I3 / PIG3 Antibody - Immunohistochemical analysis of PIG3 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µl/$412
TP53I3 / PIG3 Antibody - Western Blot: The cell lysates (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human TP53I3 antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
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TP53I3 / PIG3 Mouse anti-Human Monoclonal (AT1C9) Antibody
Human
ELISA, WB
Unconjugated
50 µl/$303; 100 µl/$365
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal (aa174-203) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal (aa174-203) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
TP53I3 / PIG3 Rabbit anti-Human Polyclonal (aa174-203) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
TP53I3 / PIG3 Rabbit anti-Human Polyclonal (aa174-203) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal (aa174-203) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal (aa174-203) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
TP53I3 / PIG3 Antibody - Western blot analysis of lysates from 293 cells, using QORX Antibody. The lane on the right is blocked with the synthesized peptide.
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal (aa241-290) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
TP53I3 / PIG3 Antibody - Western blot of PIG-3 monoclonal antibody on Jurkat lysate at 10 ug/ml on Jurkat lysate.
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TP53I3 / PIG3 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µg/$466
TP53I3 / PIG3 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TP53I3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TP53I3.
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TP53I3 / PIG3 Mouse anti-Human Monoclonal (OTI3E3) Antibody
Human
WB
Unconjugated
100 µl/$434
TP53I3 / PIG3 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TP53I3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TP53I3.
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TP53I3 / PIG3 Mouse anti-Human Monoclonal (Carrier-free) (OTI3E3) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
TP53I3 / PIG3 Antibody - Western blot of anti-PIG3 antibody on RKO cells transfected with pCEP4 without insert (1), transfected with pCEP4-PIG3 (2), under control conditions (3) and treated with Adriamycin to activate wild-type p53 (4). Also used on MCF-7 cells transfected with pCEP4 without insert (5) and pCEP4-PIG3 (6).
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$466
TP53I3 / PIG3 Antibody - TP53I3 / PIG3 antibody Western Blot of MCF7.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal (aa163-212) Antibody
Human
WB
Unconjugated
100 µl/$424
TP53I3 / PIG3 Antibody - TP53I3 / PIG3 antibody Western Blot of HepG2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TP53I3 / PIG3 Rabbit anti-Human Polyclonal (aa189-238) Antibody
Human
WB
Unconjugated
100 µl/$424
Viewing 1-25 of 34 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).