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TP / Thymidine Phosphorylase is an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified.
|Gene Name:||thymidine phosphorylase|
|Synonyms:||TYMP, ECGF1, HPD-ECGF, MEDPS1, MNGIE, MTDPS1, PD-ECGF, Thymidine phosphorylase, PDECGF, ECGF, Gliostatin, TdRPase, TP|
|Target Sequences:||NM_001953 NP_001944.1 P19971|
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