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TOR1AIP1 / LAP1

torsin A interacting protein 1

Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.

Gene Name: torsin A interacting protein 1
Synonyms: TOR1AIP1, LAP1B, Lamin-associated protein 1B, LAP1, Torsin A interacting protein 1
Target Sequences: Q5JTV8 Q5JTV8

Publications (1)

1
Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathy. Fichtman B, Zagairy F, Biran N, Barsheshet Y, Chervinsky E, Ben Neriah Z, Shaag A, Assa M, Elpeleg O, Harel A, Spiegel R. Nature communications. 2019 February;10:605. [Full Text Article] [PubMed:30723199] [PMC:PMC6363790] Related Antibodies: LS-C288839.

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
TOR1AIP1 / LAP1 (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
TOR1AIP1 / LAP1 Protein - Purified recombinant protein TOR1AIP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
66.1 kDa
20 µg/$1,107
TOR1AIP1 / LAP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
66.1 kDa
100 µg/$710
TOR1AIP1 / LAP1 Protein - 12.5% SDS-PAGE of human TOR1AIP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
78.8 kDa
2 µg/$439
TOR1AIP1 / LAP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
66.1 kDa
20 µg/$215
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).