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TOR1AIP1 / LAP1

torsin A interacting protein 1

Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.

Gene Name:	torsin A interacting protein 1
Synonyms:	TOR1AIP1, LAP1B, Lamin-associated protein 1B, LAP1, Torsin A interacting protein 1
Target Sequences:	Q5JTV8 Q5JTV8

Publications (1)

Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathy. Fichtman B, Zagairy F, Biran N, Barsheshet Y, Chervinsky E, Ben Neriah Z, Shaag A, Assa M, Elpeleg O, Harel A, Spiegel R. Nature communications. 2019 February;10:605. [Full Text Article] [PubMed:30723199] [PMC:PMC6363790] Related Antibodies: LS-C288839.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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