TOR1A / Torsin A

torsin family 1, member A (torsin A)

Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues.

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Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

TOR1A / Torsin A (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human TOR1A / Torsin A Protein (Recombinant His) - LS-G2270

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Mouse TOR1A / Torsin A Protein (Recombinant His-T7) (aa41-333) - LS-G25773

Source:

E. coli

Tag:

His-T7

Molecular Weight:

37.5 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Human TOR1A / Torsin A Protein (Recombinant His-T7) (aa33-321) - LS-G25772

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.7 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human TOR1A / Torsin A Protein (Recombinant GST) (Full Length) - LS-G28275

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

62.26 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TOR1A / Torsin A Protein (Recombinant GST, N-terminus) (aa1-332) - LS-G58392

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TOR1A / Torsin A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67553

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.6 kDa

Price:

20 µg/$1,107

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Human TOR1A / Torsin A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80130

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.6 kDa

Price:

20 µg/$150

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TOR1A / Torsin A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98919

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.6 kDa

Price:

100 µg/$494

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