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Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region.
Gene Name: | TOX high mobility group box family member 3 |
Synonyms: | TOX3, CAGF9, TNRC9 |
Target Sequences: | U80736 AAB91435.1 O15405 |
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