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TNNT2 / CTNT

troponin T type 2 (cardiac)

TNNT2 / CTNT is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Gene Name: troponin T type 2 (cardiac)
Synonyms: TNNT2, Cardiomyopathy, hypertrophic 2, CMPD2, CMD1D, CMH2, Cardiac muscle troponin T, Cardiac Troponin T, LVNC6, TnTC, Troponin T type 2 (cardiac), Troponin T, cardiac muscle, Troponin T2, cardiac, CTnT, RCM3
Target Sequences: NM_000364 NP_000355.2 P45379

Publications (1)

1
Dual mRNA therapy restores metabolic function in long-term studies in mice with propionic acidemia. Lei Jiang, Ji-Sun Park, Ling Yin, Rodrigo Laureano, Eric Jacquinet, Jinsong Yang, Shi Liang, Andrea Frassetto, Jenny Zhuo, Xinhua Yan, Xuling Zhu, Steven Fortucci, Kara Hoar, Cosmin Mihai, Christopher Tunkey, Vlad Presnyak, Kerry E Benenato, Christine M Lukacs, Paolo G V Martini, Lin T Guey. Nature communications. 2020 October;11:5339. [Full Text Article] [PubMed:33087718] [PMC:PMC7578066]

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Antibodies (173)
Primary (173)
TNNT2 / CTNT (173)
Human (150)
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rabbit (60)
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No (173)
TNNT2 / CTNT Antibody - Anti-TNNT2 / CTnT antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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Cancer
TNNT2 / CTNT Mouse anti-Rabbit Monoclonal Antibody
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Rat, Horse, Human, Monkey
IF, IHC, IHC-P
Unconjugated
50 µl/$555
TNNT2 / CTNT Antibody - Anti-TNNT2 / CTnT antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Cancer
TNNT2 / CTNT Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, SwELISA
Unconjugated
0.1 mg/$485
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TNNT2 / CTNT Chicken anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
1 mg/$469
TNNT2 / CTNT Antibody - Anti-TNNT2 / CTnT antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Cancer
TNNT2 / CTNT Mouse anti-Human Monoclonal (aa100-200) Antibody
Fish, Pig, Cat, Rat, Rabbit, Mouse, Goat, Dog, Bovine, Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$495
TNNT2 / CTNT Antibody - Anti-TNNT2 / CTnT antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Cancer
TNNT2 / CTNT Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, SwELISA
Unconjugated
0.1 mg/$485
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TNNT2 / CTNT Mouse anti-Rabbit Monoclonal Antibody
Chicken, Rabbit, Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$564
TNNT2 / CTNT Antibody - TNNT2 / CTnT antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNNT2 / CTNT Rabbit anti-Human Polyclonal (aa72-121) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
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TNNT2 / CTNT Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$1,167
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TNNT2 / CTNT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
TNNT2 / CTNT Antibody - IHC of paraffin-embedded Human adult heart tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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TNNT2 / CTNT Mouse anti-Human Monoclonal (OTI7A1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
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TNNT2 / CTNT Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
TNNT2 / CTNT Antibody - Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.0) at 110C for 10 min. (1:200)
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TNNT2 / CTNT Mouse anti-Human Monoclonal (UMAB205) Antibody
Human
IHC, PMA, WB
Unconjugated
100 µl/$493
TNNT2 / CTNT Antibody - Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.0) at 110C for 10 min. (1:200)
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TNNT2 / CTNT Mouse anti-Human Monoclonal (Carrier-free) (UMAB205) Antibody
Human
IHC, PMA, WB
Unconjugated, Carrier-free
100 µg/$539
TNNT2 / CTNT Antibody - IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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TNNT2 / CTNT Mouse anti-Human Monoclonal (OTI3H2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
TNNT2 / CTNT Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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TNNT2 / CTNT Mouse anti-Human Monoclonal (Carrier-free) (OTI3H2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TNNT2 / CTNT Antibody - IHC of paraffin-embedded Human adult heart tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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TNNT2 / CTNT Mouse anti-Human Monoclonal (OTI3C6) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
TNNT2 / CTNT Antibody - Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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TNNT2 / CTNT Mouse anti-Human Monoclonal (Carrier-free) (OTI3C6) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TNNT2 / CTNT Antibody - IHC of paraffin-embedded Human adult heart tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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TNNT2 / CTNT Mouse anti-Human Monoclonal (OTI3C3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
TNNT2 / CTNT Antibody - Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
Select
TNNT2 / CTNT Mouse anti-Human Monoclonal (Carrier-free) (OTI3C3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TNNT2 / CTNT Antibody - Western blot using troponin T2 monoclonal antibody against human troponin T2 (AA: 88-249) recombinant protein. (Expected MW is 25.1 kDa)
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TNNT2 / CTNT Mouse anti-Human Monoclonal (1G1) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
TNNT2 / CTNT Antibody - Immunohistochemistry of Troponin T-C antibody
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TNNT2 / CTNT Rabbit anti-Human Polyclonal (131-180 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TNNT2 / CTNT Antibody - IHC of paraffin-embedded Human adult heart tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Select
TNNT2 / CTNT Mouse anti-Human Monoclonal (OTI7B1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
TNNT2 / CTNT Antibody - IHC of paraffin-embedded Human adult heart tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Select
TNNT2 / CTNT Mouse anti-Human Monoclonal (OTI7D2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
TNNT2 / CTNT Antibody - IHC of paraffin-embedded Human adult heart tissue using anti-TNNT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Select
TNNT2 / CTNT Mouse anti-Human Monoclonal (OTI8B5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
TNNT2 / CTNT Antibody - Immunohistochemistry of paraffin-embedded Rat heart using TNNT2 Polyclonal Antibody at dilution of 1:50.
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TNNT2 / CTNT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$250; 60 µl/$286; 120 µl/$349; 200 µl/$439
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).