TNNI2

troponin I type 2 (skeletal, fast)

TNNI2 is a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

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Products

Proteins (15)

Type

Over-Expression Lysate (6)

Recombinant (9)

Target

TNNI2 (15)

Publications

No (15)

Tag

10His, N-terminus + Myc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (3)

His, N-Terminal (1)

Myc-DDK (Flag) (8)

Species

Human (9)

Mouse (2)

Rat (1)

Source

293T Cells (3)

E. coli (5)

HEK 293 Cells (5)

Wheat Germ Extract (2)

Purification

Purified (4)

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Human TNNI2 Protein (Recombinant His) - LS-G2029

Source:

E. coli

Tag:

His

Price:

20 µg/$361; 100 µg/$739; 4 µg/$261

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Mouse TNNI2 Protein (Recombinant His) (aa1-182) - LS-G15222

Source:

E. coli

Tag:

His

Molecular Weight:

22.9 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Mouse TNNI2 Protein (Recombinant 10His, N-terminus + Myc, C-terminus) (Full Length) - LS-G137127

Source:

E. coli

Tag:

10His, N-terminus + Myc, C-terminus

Molecular Weight:

28.2 kDa

Price:

20 µg/$405; 1 mg/$1,679; 100 µg/$598

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TNNI2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126843

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.2 kDa

Price:

100 µg/$494

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TNNI2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126846

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.2 kDa

Price:

100 µg/$494

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Human TNNI2 Protein (Recombinant GST, N-terminus) (aa2-100) - LS-G60392

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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TNNI2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117444

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.2 kDa

Price:

100 µg/$494

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Human TNNI2 Protein (Recombinant GST) (Full Length) - LS-G30742

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

47.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TNNI2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67205

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.2 kDa

Price:

20 µg/$1,107

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Human TNNI2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67204

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.2 kDa

Price:

20 µg/$1,107

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Human TNNI2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79331

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.2 kDa

Price:

20 µg/$150

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Human TNNI2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79332

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.2 kDa

Price:

20 µg/$150

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Human TNNI2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79333

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.2 kDa

Price:

20 µg/$150

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Human TNNI2 Protein (Recombinant His, N-Terminal) (Met1-Ser182) - LS-G132578

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

26kDa

Price:

10 µg/$268; 50 µg/$362; 200 µg/$722; 100 µg/$577; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934

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Rat TNNI2 Protein (Recombinant His) (aa1-182) - LS-G15224

Source:

E. coli

Tag:

His

Molecular Weight:

22.8 kDa

Price:

10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142

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