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TNNC1 / Cardiac Troponin C

troponin C type 1 (slow)

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.

Gene Name: troponin C type 1 (slow)
Synonyms: TNNC1, CMD1Z, Cardiac troponin C, CMH13, Troponin C type 1 (slow), TN-C, TNNC, Troponin C, slow, Troponin C1, slow
Target Sequences: NM_003280 NP_003271.1 P63316

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).