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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNK1

tyrosine kinase, non-receptor, 1

TNK1 belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: tyrosine kinase, non-receptor, 1
Family/Subfamily: Protein Kinase , ACK
Synonyms: TNK1, CD38 negative kinase 1
Target Sequences: NM_003985 NP_003976.2 Q13470

Filtered By: None
Target
TNK1 (44)
Reactivity
Human (34)
Mouse (14)
Rat (1)
Chimpanzee (3)
Application
IHC (22)
IHC-P (7)
WB (43)
ELISA (32)
Peptide-ELISA (1)
Host
rabbit (34)
mouse (10)
Isotype
IgG (26)
IgG1 (1)
IgG1,k (9)
Clonality
monoclonal mc (11)
polyclonal pc (33)
Clone
170CT7.5.4 (7)
1B5G3 (1)
D46E7 (1)
Format
AP Conjugated (4)
APC Conjugated (4)
Azide-free (4)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (17)
Epitope
aa256-286 (8)
Internal (7)
aa517-566 (4)
aa421-434 (2)
aa554-588 (1)
pTyr277 (1)
Publications
No (44)
Showing 1-25 of 44 results

TNK1 Antibody (aa421-434) IHC-plus™ LS-B526
Rabbit Polyclonal to Mouse TNK1
Mouse, Human
IHC IHC-P
Unconjugated
100µl  $425.00
Anti-TNK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-TNK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

TNK1 Antibody (phospho-Tyr277, clone D46E7) LS-C184140
Rabbit Monoclonal [clone D46E7] (IgG) to Human TNK1
Mouse, Rat, Human
WB
Unconjugated
100µl  $575.00

TNK1 Antibody (aa517-566) IHC-plus™ LS-B11489
Rabbit Polyclonal to Human TNK1
Human
IHC IHC-P WB
Unconjugated
50µg  $485.00
Anti-TNK1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
TNK1 antibody Western Blot of RPMI-8226 cell lysate. TNK1 is supported by BioGPS gene expression data to be expressed in RPMI 8226.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-TNK1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
TNK1 antibody Western Blot of RPMI-8226 cell lysate. TNK1 is supported by BioGPS gene expression data to be expressed in RPMI 8226.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TNK1 Antibody (Internal) LS-C325849
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
Unconjugated
200µl  $530.00

TNK1 Antibody (Internal, Biotin) LS-C218040
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
Biotin Conjugated
200µl  $680.00

TNK1 Antibody (Internal, FITC) LS-C218041
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
FITC Conjugated
200µl  $680.00

TNK1 Antibody (Internal, AP) LS-C218039
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
AP Conjugated
200µl  $680.00

TNK1 Antibody (Internal, PE) LS-C218043
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
PE Conjugated
200µl  $680.00

TNK1 Antibody (Internal, Azide-free, HRP) LS-C218044
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

TNK1 Antibody (Internal, APC) LS-C218038
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
APC Conjugated
200µl  $680.00

TNK1 Antibody LS-C661140
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
Unconjugated
100µg  $435.00

TNK1 Antibody LS-C403665
Rabbit Polyclonal (IgG) to Human TNK1
Mouse, Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human liver cancer using TNK1 Polyclonal Antibody at dilution of 1:20.
Western blot analysis of Human fetal brain tissue, using TNK1 Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry of Human liver cancer using TNK1 Polyclonal Antibody at dilution of 1:20.
Western blot analysis of Human fetal brain tissue, using TNK1 Polyclonal Antibody at dilution of 1:400.

TNK1 Antibody LS-C160086
Mouse Monoclonal (IgG1,k) to Human TNK1
Mouse, Human
IHC IHC-P WB
Unconjugated
100µl  $305.00
TNK1 Monoclonal( Ascites) immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
TNK1 Antibody western blot of mouse brain cell line lysates (15 ug/lane). The TNK1 antibody detected the TNK1 protein (arrow). (1:500)
TNK1 Monoclonal( Ascites) immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
TNK1 Antibody western blot of mouse brain cell line lysates (15 ug/lane). The TNK1 antibody detected the TNK1 protein (arrow). (1:500)

TNK1 Antibody (clone 170CT7.5.4) LS-C319214
Mouse Monoclonal [clone 170CT7.5.4] (IgG1,k) to Mouse TNK1
Mouse
ELISA WB
Unconjugated
200µl  $530.00

TNK1 Antibody (clone 170CT7.5.4, Biotin) LS-C212539
Mouse Monoclonal [clone 170CT7.5.4] (IgG1,k) to Mouse TNK1
Mouse
ELISA WB
Biotin Conjugated
200µl  $680.00

TNK1 Antibody (clone 170CT7.5.4, APC) LS-C212538
Mouse Monoclonal [clone 170CT7.5.4] (IgG1,k) to Mouse TNK1
Mouse
ELISA WB
APC Conjugated
200µl  $680.00

TNK1 Antibody (aa256-286, Biotin) LS-C220849
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
Biotin Conjugated
200µl  $680.00

TNK1 Antibody (aa256-286, FITC) LS-C220850
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
FITC Conjugated
200µl  $680.00

TNK1 Antibody (aa256-286, APC) LS-C220848
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
APC Conjugated
200µl  $680.00

TNK1 Antibody (aa256-286, Azide-free, HRP) LS-C220851
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

TNK1 Antibody (aa256-286, PE) LS-C220852
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
PE Conjugated
200µl  $680.00

TNK1 Antibody (aa256-286, AP) LS-C220847
Rabbit Polyclonal (IgG) to Human TNK1
Human
ELISA IHC WB
AP Conjugated
200µl  $680.00

TNK1 Antibody (aa256-286) LS-C99394
Rabbit Polyclonal to Human TNK1
Human
IHC IHC-P WB
Unconjugated
400µl  $305.00
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Western blot of anti-TNK1 antibody in HeLa cell line lysate. Dilution of anti-TNK1 was 1:100; dilution of secondary antibody (goat anti-rabbit-HRP) was 1:7000. Data and protocol courtesy of Dr. Richard Lu, Partners HealthCare System at Harvard University.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Western blot of anti-TNK1 antibody in HeLa cell line lysate. Dilution of anti-TNK1 was 1:100; dilution of secondary antibody (goat anti-rabbit-HRP) was 1:7000. Data and protocol courtesy of Dr. Richard Lu, Partners HealthCare System at Harvard University.

TNK1 Antibody (aa421-434) LS-C40722
Rabbit Polyclonal (IgG) to Mouse TNK1
Mouse
ELISA WB
Unconjugated
100µg 100µl 1mg/ml  $275.00

TNK1 Antibody (clone 1B5G3) LS-C108736
Mouse Monoclonal [clone 1B5G3] (IgG1) to Human TNK1
Human
ELISA WB
Unconjugated
100µl  $315.00
Western blot using TNK1 mouse monoclonal antibody against truncated TNK1-His recombinant protein (1).
Western blot using TNK1 mouse monoclonal antibody against truncated TNK1-His recombinant protein (1).
Showing 1-25 of 44 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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