Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

TNFSF14 / LIGHT

tumor necrosis factor (ligand) superfamily, member 14

TNFSF14 / LIGHT is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Gene Name: tumor necrosis factor (ligand) superfamily, member 14
Family/Subfamily: TNF , not assigned-TNF
Synonyms: TNFSF14, CD258 antigen, CD258, Delta transmembrane LIGHT, Herpesvirus entry mediator A, HVEM-L, TR2, HVEML, LIGHT, LTg
Target Sequences: NM_003807 NP_003798.2 O43557

Publications (1)

1
Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies. Seungwon An, Ilangovan Raju, Bayasgalan Surenkhuu, Ji-Eun Kwon, Shilpa Gulati, Muge Karaman, Anubhav Pradeep, Satyabrata Sinha, Christine Mun, Sandeep Jain. The ocular surface. 2019 July;17:589-614. [Full Text Article] [PubMed:30965123] [PMC:PMC6721977] Related Antibodies: LS-C118682.

☰ Filters
Products
Proteins (17)
Over-Expression Lysate (2)
Recombinant (15)
TNFSF14 / LIGHT (17)
No (17)
6His, N-terminus (1)
DDK (Flag) (1)
GST (2)
GST, N-terminus (1)
His (2)
His,N-terminus (1)
His-S (2)
mFc, N-terminus (1)
Myc-DDK (Flag) (3)
Human (12)
Mouse (3)
Rat (1)
293T Cells (1)
CHO Cells (2)
E. coli (4)
HEK 293 Cells (2)
High Five Cells (1)
Human Cells (2)
Mammalian Cells (2)
Wheat Germ Extract (3)
Purified (5)
Low endotoxin level (8)
Biologically active (3)
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
20.1 kDa
5 µg/$268; 20 µg/$349
TNFSF14 / LIGHT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.35 kDa
100 µg/$494
TNFSF14 / LIGHT Protein - 12.5% SDS-PAGE of human TNFSF14 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
45.21 kDa
10 µg/$479; 25 µg/$670
TNFSF14 / LIGHT Protein - 12.5% SDS-PAGE of human TNFSF14 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
48.8 kDa
10 µg/$479; 25 µg/$670
TNFSF14 / LIGHT Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TNFSF14 / LIGHT Protein - Purified recombinant protein TNFSF14 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
22 kDa
20 µg/$1,107
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
20.4 kDa
100 µg/$666
TNFSF14 / LIGHT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.35 kDa
20 µg/$150
Select
High Five Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
19.3 kDa
3 µg/$268; 15 µg/$349
Select
Mammalian Cells
mFc, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
43.3 kDa
10 µg/$266; 50 µg/$361
TNFSF14 / LIGHT Protein - Recombinant mouse LIGHT's cytotoxic effect on HT-29 human colon adenocarcinoma cells.
Select
CHO Cells
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 189 amino acid recombinant protein has a predicted molecular mass of approximately 20.5 kD. The DTT-reduced and non-reduced protein migrate at approximately 30 and 28 kD respectively by SDS-PAGE. The predicted N-terminal amino acid is His.
25 µg/$375
Select
Mammalian Cells
His,N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
18.2 kDa
10 µg/$288; 50 µg/$436
Select
CHO Cells
DDK (Flag)
Less than 0.01 EU/µg protein (determined by LAL method).
~25kDa (SDS-PAGE)
10 µg/$295
Select
Human Cells
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
18.2kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
TNFSF14 / LIGHT Protein - Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 14 By SDS-PAGE
Select
E. coli
His-S
25.4 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
TNFSF14 / LIGHT Protein - Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 14 By SDS-PAGE
Select
E. coli
His
21.5 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
TNFSF14 / LIGHT Protein - Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 14 By SDS-PAGE
Select
E. coli
His-S
26.5 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
Viewing 1-17 of 17 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).