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TNFSF14 / LIGHT

tumor necrosis factor (ligand) superfamily, member 14

TNFSF14 / LIGHT is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Gene Name: tumor necrosis factor (ligand) superfamily, member 14
Family/Subfamily: TNF , not assigned-TNF
Synonyms: TNFSF14, CD258 antigen, CD258, Delta transmembrane LIGHT, Herpesvirus entry mediator A, HVEM-L, TR2, HVEML, LIGHT, LTg
Target Sequences: NM_003807 NP_003798.2 O43557

Publications (1)

1
Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies. Seungwon An, Ilangovan Raju, Bayasgalan Surenkhuu, Ji-Eun Kwon, Shilpa Gulati, Muge Karaman, Anubhav Pradeep, Satyabrata Sinha, Christine Mun, Sandeep Jain. The ocular surface. 2019 July;17:589-614. [Full Text Article] [PubMed:30965123] [PMC:PMC6721977] Related Antibodies: LS-C118682.

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Antibodies (65)
Primary (65)
TNFSF14 / LIGHT (65)
Human (46)
Mouse (18)
Rat (17)
Gibbon (3)
Horse (3)
Monkey (3)
IHC (8)
IHC-P (9)
WB (57)
Flo (6)
ELISA (19)
ICC (5)
IF (10)
IP (1)
Peptide-ELISA (3)
rabbit (49)
mouse (15)
goat (1)
Product Group
IHCPlus (3)
IgG (21)
IgG1,k (2)
IgG2a,k (1)
IgG2b (4)
monoclonal mc (15)
polyclonal pc (50)
4E3 (1)
7-3 (7) (2)
7B9E12 (1)
7B9F12 (1)
7B9H9 (1)
8D4 (1)
APC (4)
APC Conjugated (5)
Azide-free (1)
Biotin Conjugated (7)
Cy3 Conjugated (4)
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FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (7)
Unconjugated (26)
aa62-240 (15)
aa51-239 (8)
aa58-239 (8)
aa66-94 (7)
C-Terminus (4)
30-110 aa, Internal (1)
Internal (1)
aa51-100 (1)
aa90-103 (1)
No (64)
Yes (1)
TNFSF14 / LIGHT Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal (aa62-240) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
TNFSF14 / LIGHT Antibody - Immunoperoxidase of monoclonal antibody to TNFSF14 on formalin-fixed paraffin-embedded human spleen. [antibody concentration 3 ug/ml]
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TNFSF14 / LIGHT Mouse anti-Human Monoclonal (4E3) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$423
TNFSF14 / LIGHT Antibody - Western Blot (non-reducing) of TNFSF14 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
TNFSF14 / LIGHT Antibody - Western Blot (non-reducing) of TNFSF14 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
TNFSF14 / LIGHT Antibody - Staining of PMA and ionomycin-stimulated normal human peripheral blood cells with APC anti-human CD8a (RPA-T8) (LS-C107300) and 0.25 ug of PE Mouse IgG1, K isotype control (left) or PE anti-human CD258 (7-3) (right). Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFSF14 / LIGHT Mouse anti-Human Monoclonal (PE) (7-3 (7)) Antibody
Human
Flo
PE Conjugated
100 Tests/$568
TNFSF14 / LIGHT Antibody - TNFSF14 / LIGHT antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Horse, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
TNFSF14 / LIGHT Antibody - Immunofluorescence analysis of HeLa cells, using TNF14 Antibody. The picture on the right is blocked with the synthesized peptide.
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal (aa51-100) Antibody
Mouse, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
TNFSF14 / LIGHT Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
TNFSF14 / LIGHT Antibody - Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, IHC, IHC-P
Unconjugated
50 µg/$460
TNFSF14 / LIGHT Antibody - Western blot of recombinant TNFSF14 / LIGHT.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFSF14 / LIGHT Rabbit anti-Mouse Polyclonal (aa51-239) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
TNFSF14 / LIGHT Antibody - Western blot of recombinant TNFSF14 / LIGHT.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFSF14 / LIGHT Rabbit anti-Mouse Polyclonal (aa51-239) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
TNFSF14 / LIGHT Antibody - Western blot of recombinant TNFSF14 / LIGHT.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFSF14 / LIGHT Rabbit anti-Mouse Polyclonal (aa51-239) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$338; 200 µl/$392; 500 µl/$573; 1 ml/$698; 2 ml/$936; 5 ml/$1,588
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$341
TNFSF14 / LIGHT Antibody - Immunohistochemistry of LIGHT in human lymphoma tissue with LIGHT antibody at 5 ug/mL.
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TNFSF14 / LIGHT Mouse anti-Human Monoclonal (7B9F12) Antibody
Human
ELISA, Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$502
TNFSF14 / LIGHT Antibody - Immunohistochemistry of LIGHT in human lymphoma tissue with LIGHT antibody at 5 ug/mL.
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TNFSF14 / LIGHT Mouse anti-Human Monoclonal (7B9E12) Antibody
Human
ELISA, Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$502
TNFSF14 / LIGHT Antibody - Immunohistochemistry of LIGHT in human lymphoma tissue with LIGHT antibody at 5 ug/mL.
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TNFSF14 / LIGHT Mouse anti-Human Monoclonal (7B9H9) Antibody
Human
ELISA, Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$502
TNFSF14 / LIGHT Antibody - Immunohistochemistry of LIGHT in human lymphoma tissue with LIGHT antibody at 5 ug/mL.
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TNFSF14 / LIGHT Mouse anti-Human Monoclonal (8D4) Antibody
Human
ELISA, Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$502
TNFSF14 / LIGHT Antibody - Western blot of TNFSF14 antibody at 1:500 Line1:HeLa whole cell lysate Line2:Raw264.7 whole cell lysate.
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
TNFSF14 / LIGHT Antibody - Western blot of recombinant TNFSF14 / LIGHT.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal (aa62-240) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$325; 200 µl/$375; 500 µl/$539; 1 ml/$632; 2 ml/$867; 5 ml/$1,439
TNFSF14 / LIGHT Antibody - TNFSF14 / LIGHT antibody immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing cytoplasmic and membrane staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
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TNFSF14 / LIGHT Goat anti-Human Polyclonal (aa90-103) Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µg/$503
TNFSF14 / LIGHT Antibody - Anti-Murine LIGHT Western Blot Unreduced
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TNFSF14 / LIGHT Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
TNFSF14 / LIGHT Antibody - Biotinylated Anti-Murine LIGHT Western Blot Unreduced
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TNFSF14 / LIGHT Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
TNFSF14 / LIGHT Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TNFSF14 / LIGHT Antibody - Immunofluorescence of LIGHT antibody
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TNFSF14 / LIGHT Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody
Mouse, Human
ELISA, IF
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TNFSF14 / LIGHT Antibody - Peptide - + Immunofluorescence analysis of HeLa cells, using TNF14 antibody.
Select
TNFSF14 / LIGHT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
100 µg/$357
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).