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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNFSF13 / APRIL

tumor necrosis factor (ligand) superfamily, member 13

TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.

Gene Name: tumor necrosis factor (ligand) superfamily, member 13
Family/Subfamily: TNF , not assigned-TNF
Synonyms: TNFSF13, APRIL, CD256, CD256 antigen, TALL-2, TALL2, ZTNF2, TNF-related death ligand 1, TRDL-1, UNQ383/PRO715
Target Sequences: NM_003808 NP_003799.1 O75888

Publications (2)

1
Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia. Robak OH, Heimesaat MM, Kruglov AA, Prepens S, Ninnemann J, Gutbier B, Reppe K, Hochrein H, Suter M, Kirschning CJ, Marathe V, Buer J, Hornef MW, Schnare M, Schneider P, Witzenrath M, Bereswill S, Steinhoff U, Suttorp N, Sander LE, Chaput C, Opitz B. The Journal of clinical investigation. 2018 August;128:3535-3545. [Full Text Article] [PubMed:29771684] [PMC:PMC6063483]
2
Development and characterization of APRIL antagonistic monoclonal antibodies for treatment of B-cell lymphomas. Guadagnoli M, Kimberley FC, Phan U, Cameron K, Vink PM, Rodermond H, Eldering E, Kater AP, van Eenennaam H, Medema JP. Blood. 2011 Jun;117:6856-65. [Full Text Article] [PubMed:21543761] Related Antibodies: LS-C18687, LS-C18659, LS-C18658.

Viewing 1-25 of 112 items
TNFSF13 / APRIL Antibody - Anti-APRIL antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
Select
(1) Publication(s)
Mouse Monoclonal (IgG1) to Human TNFSF13 / APRIL
Human
ELISA, IP, WB
Unconjugated
100µg   1mg/ml   $415.00
TNFSF13 / APRIL Antibody - Anti-APRIL antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Human
IHC, IHC-P, WB
Unconjugated
50µg   0.5mg/ml   $425.00
Select
(1) Publication(s)
Mouse Monoclonal (IgG1) to Human TNFSF13 / APRIL
Human
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
100µg   1mg/ml   $395.00
TNFSF13 / APRIL Antibody - Anti-APRIL antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
Select
(1) Publication(s)
Mouse Monoclonal [clone Aprily-1] (IgG1) to Human TNFSF13 / APRIL
Human
Flo, IP, WB
Unconjugated
100µg   1mg/ml   $395.00
Select
Rat Monoclonal (IgG2a) to Human TNFSF13 / APRIL
Mouse, Human
ELISA, Flo, ICC
Unconjugated
100µg   1mg/ml   $405.00
TNFSF13 / APRIL Antibody - Anti-APRIL antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $545.00
TNFSF13 / APRIL Antibody - Detection limit for recombinant GST tagged TNFSF13 is 1 ng/ml as a capture antibody.
Select
Mouse Monoclonal [clone 4A11] (IgG2a,k) to Human TNFSF13 / APRIL
Human
ELISA, WB
Unconjugated
100µg   $365.00
Select
Rabbit Polyclonal to Human TNFSF13 / APRIL
Human
ELISA, WB
Unconjugated
50µg   $285.00; 100µg   $325.00
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Human
ELISA, WB
Unconjugated
50µg   $405.00; 100µg   $560.00
TNFSF13 / APRIL Antibody - Immunohistochemical analysis of CD256 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
Rabbit Polyclonal to Human TNFSF13 / APRIL
Mouse, Dog, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $245.00
TNFSF13 / APRIL Antibody
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
TNFSF13 / APRIL Antibody
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
TNFSF13 / APRIL Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   $285.00; 100µl   $385.00
TNFSF13 / APRIL Antibody - Western blot of HeLa cell lysate using TALL-2 Antibody
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Rabbit Polyclonal to Human TNFSF13 / APRIL
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
100µg   $305.00
TNFSF13 / APRIL Antibody
Select
Rabbit Polyclonal to Mouse TNFSF13 / APRIL
Mouse
WB
Biotin Conjugated
100µl   0.5mg/ml   $265.00; 200µl   0.5mg/ml   $315.00; 1ml   0.5mg/ml   $560.00
TNFSF13 / APRIL Antibody - Western blot of APRIL antibody
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
TNFSF13 / APRIL Antibody - IHC of APRIL (S183) pAb in paraffin-embedded human colon carcinoma tissue.
Select
Rabbit Polyclonal to Human TNFSF13 / APRIL
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $345.00
TNFSF13 / APRIL Antibody - Immunohistochemistry of paraffin-embedded human liver cancer using TNFSF13 antibodyat dilution of 1:100 (40x lens).
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Human
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
TNFSF13 / APRIL Antibody - Western blot of TALL-2 expression in COLO205 cells
Select
Rabbit Polyclonal to Human TNFSF13 / APRIL
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100µg   $305.00
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Human
ELISA, IHC, WB
Unconjugated
100µg   $465.00
Select
Rabbit Polyclonal to Human TNFSF13 / APRIL
Human
IHC, IHC-P, WB
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
Select
Rat Monoclonal (IgG2a) to Human TNFSF13 / APRIL
Mouse, Human
Flo, ICC
Unconjugated
100µg   1mg/ml   $375.00
TNFSF13 / APRIL Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
Select
Rabbit Polyclonal (IgG) to Human TNFSF13 / APRIL
Human
ELISA, IHC, IHC-P
Unconjugated
50µl   $285.00; 100µl   $385.00

Viewing 1-25 of 112 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).