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Unfortunately, the antibody (ID:108550) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



TNFRSF10B / Killer / DR5

tumor necrosis factor receptor superfamily, member 10b

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently. Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB.

Gene Name: tumor necrosis factor receptor superfamily, member 10b
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF10B, Cytotoxic TRAIL receptor-2, CD262 antigen, DR5, Death receptor 5, KILLER, TRAIL-R2, TRICK2B, TRAILR2, TRICK2A, TRICKB, TRICK2, CD262, Fas-like protein, TRAIL receptor 2, ZTNFR9
Target Sequences: NM_147187 Q6FH58 O14763

Publications (2)

1
Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity. Lundqvist A, Abrams SI, Schrump DS, Alvarez G, Suffredini D, Berg M, Childs R. Cancer research. 2006 66:7317-25. [PubMed:16849582] Related Antibodies: LS-C40991.
2
Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma. Shi J, Tricot GJ, Garg TK, Malaviarachchi PA, Szmania SM, Kellum RE, Storrie B, Mulder A, Shaughnessy JD, Barlogie B, van Rhee F. Blood. 2008 111:1309-17. [PubMed:17947507] [PMC:PMC2214736] Related Antibodies: LS-C40990.

Filtered By: None
Target
tnfrsf10b-killer-dr5 (91)
Reactivity
Human (81)
Mouse (17)
Rat (4)
Chimpanzee (1)
Orangutan (1)
Application
IHC (4)
IHC-P (10)
WB (64)
Flo (23)
ELISA (23)
Func (3)
ICC (13)
IF (1)
IP (12)
Host
rabbit (57)
mouse (32)
goat (1)
rat (1)
Isotype
IgG (40)
IgG1 (14)
IgG1,k (11)
IgG2a (2)
Clonality
monoclonal mc (32)
polyclonal pc (59)
Clone
1B9 (1)
DJR2-2 (2-6) (1)
DJR2-2 (a.k.a. 2-6) (1)
DJR2-4 (7-8) (1)
DJR2-4 (a.k.a. 7-8) (3)
DR5-01 (1)
DR5-01-1 (3)
HS201 (6)
TR2.21 (1)
TS106 (1)
Format
AP Conjugated (3)
APC Conjugated (2)
Atto 488 Conjugated (1)
Atto 647N Conjugated (1)
Azide-free (1)
Biotin Conjugated (9)
FITC Conjugated (9)
HRP Conjugated (4)
PE Conjugated (5)
Unconjugated (57)
Epitope
Extracellular Domain (7)
aa38-87 (4)
Internal (3)
N-Terminus (3)
aa233-367 (3)
aa234-435 (3)
aa54-180 (3)
aa388-407 (2)
C-Terminus (1)
aa1-170 (1)
aa203-411 (1)
aa280-296 (1)
aa333-348 (1)
aa380-398 (1)
aa417-436 (1)
aa56-128 (1)
aa71-170 (1)
Publications
No (89)
Yes (2)
Showing 1-25 out of 91 results
Anti-TNFRSF10B / Killer / DR5 Antibody (C-Terminus) IHC-plus™ LS-B136

Rabbit Polyclonal to Human TNFRSF10B / Killer / DR5
Mouse, Human
ICC IF IHC-P WB
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (aa388-407) IHC-plus™ LS-B2074

Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5
Human
Flo ICC IHC-P WB
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (aa380-398) IHC-plus™ LS-B5086

Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5
Human
IHC-P WB
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (clone HS201) IHC-plus™ LS-B13479

Mouse Monoclonal [clone HS201] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
Flo Func ICC IHC-P IP
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (Extracellular Domain, clone DJR2-2 (2-6)) LS-C40990

Mouse Monoclonal [clone DJR2-2 (2-6)] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
Flo
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (clone HS201) IHC-plus™ LS-B12882

Mouse Monoclonal [clone HS201] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
Flo Func ICC IHC-P IP
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (Extracellular Domain, clone DJR2-4 (7-8)) LS-C40991

Mouse Monoclonal [clone DJR2-4 (7-8)] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
Flo
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (aa203-411, clone 1B9) LS-C340229

Mouse Monoclonal [clone 1B9] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
IHC-P WB
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody IHC-plus™ LS-B8498

Rabbit Polyclonal
Human
Flo IHC-P WB
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (aa280-296) LS-C40740

Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5
Human
ELISA WB
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (clone DJR2-2 (a.k.a. 2-6)) LS-C107027

Mouse Monoclonal [clone DJR2-2 (a.k.a. 2-6)] (IgG1,k) to Human TNFRSF10B / Killer / DR5
Human
Flo
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (Extracellular Domain, clone DR5-01-1, PE) LS-C46528

Mouse Monoclonal [clone DR5-01-1] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
Flo
PE Conjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (Extracellular Domain) LS-C83941

Goat Polyclonal to Human TNFRSF10B / Killer / DR5
Human
ELISA Flo IHC WB
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (clone HS201, Biotin) LS-C344763

Mouse Monoclonal [clone HS201] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
Flo Func ICC IP
Biotin Conjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (Internal) LS-C137118

Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (aa417-436, Azide-free) LS-C148093

Rabbit Polyclonal to Human TNFRSF10B / Killer / DR5
Human
Flo IHC-P WB
Unconjugated, Azide-free
Anti-TNFRSF10B / Killer / DR5 Antibody (aa71-170) LS-C307889

Mouse Monoclonal (IgG1,k) to Human TNFRSF10B / Killer / DR5
Human
ELISA IP WB
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody LS-C342028

Mouse Monoclonal to Human TNFRSF10B / Killer / DR5
Mouse, Human
ICC WB
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (aa234-435, Biotin) LS-C419642

Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5
Human
ELISA ICC WB
Biotin Conjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (aa234-435, FITC) LS-C419643

Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5
Human
ELISA ICC WB
FITC Conjugated
Anti-TNFRSF10B / Killer / DR5 Antibody LS-C411420

Mouse Monoclonal (IgG) to Human TNFRSF10B / Killer / DR5
Mouse, Human
ICC WB
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (aa1-170) LS-C36145

Rat Monoclonal (IgG2a) to Mouse TNFRSF10B / Killer / DR5
Mouse
Flo IP
Unconjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (clone HS201, FITC) LS-C344764

Mouse Monoclonal [clone HS201] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
Flo ICC
FITC Conjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (clone HS201, Atto 488) LS-C344766

Mouse Monoclonal [clone HS201] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
Flo ICC
Atto 488 Conjugated
Anti-TNFRSF10B / Killer / DR5 Antibody (clone HS201, Atto 647N) LS-C344767

Mouse Monoclonal [clone HS201] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
Flo ICC
Atto 647N Conjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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