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TMPRSS4 is a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | transmembrane protease, serine 4 |
Family/Subfamily: | Protease , Serine S1 |
Synonyms: | TMPRSS4, CAPH2, Channel-activating protease 2, MT-SP2 |
Target Sequences: | NM_019894 NP_063947.1 Q9NRS4 |
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