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TM4SF6 / TSPAN6

tetraspanin 6

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing.

Gene Name: tetraspanin 6
Family/Subfamily: Tetraspan , not assigned-Tetraspan
Synonyms: TSPAN6, A15 homolog, Tetraspanin TM4-D, Tetraspanin-6, TM4SF6, Tetraspanin 6, T245, T245 protein, Tetraspan TM4SF, TSPAN-6
Target Sequences: NM_003270 NP_003261.1 O43657

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
TM4SF6 / TSPAN6 (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
TM4SF6 / TSPAN6 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TM4SF6 / TSPAN6 Protein - 12.5% SDS-PAGE of human TSPAN6 stained with Coomassie Blue
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Wheat Germ Extract
GST
52.58 kDa
2 µg/$439
TM4SF6 / TSPAN6 Protein - Purified recombinant protein TSPAN6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
27.4 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
27.4 kDa
20 µg/$150
TM4SF6 / TSPAN6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
27.4 kDa
100 µg/$494
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).