The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing.
|Gene Name:||tetraspanin 6|
|Family/Subfamily:||Tetraspan , not assigned-Tetraspan|
|Synonyms:||TSPAN6, A15 homolog, Tetraspanin TM4-D, Tetraspanin-6, TM4SF6, Tetraspanin 6, T245, T245 protein, Tetraspan TM4SF, TSPAN-6|
|Target Sequences:||NM_003270 NP_003261.1 O43657|
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.