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TLR10

toll-like receptor 10

TLR10 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Gene Name: toll-like receptor 10
Family/Subfamily: Toll-like Receptor , not assigned-Toll-like Receptor
Synonyms: TLR10, CD290, CD290 antigen, Toll-like receptor 10
Target Sequences: NM_030956 NP_112218.2 Q9BXR5

Publications (1)

1
Cutting-Edge Report: TLR10 Plays a Role in Mediating Bacterial Peptidoglycan-Induced Trophoblast Apoptosis. Bai JZ, Lipski J. American journal of reproductive immunology (New York, N.Y. : 1989). 2012 (IHC, WB; Human) [PubMed:23279063] [PMC:PMC3620725]

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Products
Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
TLR10 (10)
Product Group
Coronavirus Antibodies Proteins cDNAs (1)
No (10)
10His, N-terminus (1)
10His-SUMO, N-terminus + Myc, C-terminus (1)
GST (1)
GST, N-terminus (1)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (7)
Rat (1)
293T Cells (2)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
TLR10 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TLR10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
94.4 kDa
100 µg/$710
TLR10 Protein
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GST
114.84kDa
10 µg/$479; 25 µg/$670
TLR10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
94.4 kDa
20 µg/$215
TLR10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
94.4 kDa
20 µg/$215
TLR10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
94.4 kDa
100 µg/$710
TLR10 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus
100 µg/$1,128; 20 µg/$721
TLR10 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His-SUMO, N-terminus + Myc, C-terminus
100 µg/$1,128; 20 µg/$721
TLR10 Protein - Recombinant Toll Like Receptor 10 By SDS-PAGE
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E. coli
His-GST
52.3 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
TLR10 Protein - Recombinant Toll Like Receptor 10 By SDS-PAGE
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E. coli
His-T7
30.1 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).