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TIPRL / TIP

TIP41, TOR signaling pathway regulator-like (S. cerevisiae)

May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.

Gene Name:	TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
Synonyms:	TIPRL, Type 2A-interacting protein, DJ69E11.3, RP1-69E11.1, TIP, TIP41, TIP41-like protein
Target Sequences:	NP_690866.1 O75663

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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