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TIMD4 / TIM4 / TIM-4
T-cell immunoglobulin and mucin domain containing 4
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1.
| Gene Name: | T-cell immunoglobulin and mucin domain containing 4 |
| Synonyms: | TIMD4, SMUCKLER, TIM-4, T-cell membrane protein 4, TIM4, TIMD-4, TIM 4 |
| Target Sequences: | NM_138379 NP_612388.2 Q96H15 |
Publications (3)
1
The emerging role of T cell immunoglobulin mucin-1 in the mechanism of liver ischemia and reperfusion injury in the mouse. Uchida Y, Ke B, Freitas MC, Ji H, Zhao D, Benjamin ER, Najafian N, Yagita H, Akiba H, Busuttil RW, Kupiec-Weglinski JW. Hepatology (Baltimore, Md.). 2010 51:1363-72. (IHC-P; Mouse)
[Full Text Article]
[PubMed:20091883]
[PMC:PMC3066468]
Related Antibodies: LS-B1413.
2
Dual role of phosphatidylserine and its receptors in osteoclastogenesis. Jee-Hae Kang , Hyun-Mi Ko , Geum-Dong Han, Su-Young Lee, Jung-Sun Moon, Min-Seok Kim, Jeong-Tae Koh, Sun-Hun Kim. Cell death & disease. 2020 July;11:497. [Full Text Article]
[PubMed:32612123]
[PMC:PMC7330034]
Related Antibodies: LS-B598.
3
Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE. Joann Chongsaritsinsuk , Alexandra D Steigmeyer , Keira E Mahoney , Mia A Rosenfeld , Taryn M Lucas, Courtney M Smith, Alice Li, Deniz Ince, Fiona L Kearns, Alexandria S Battison, Marie A Hollenhorst, D Judy Shon, Katherine H Tiemeyer, Victor Attah, Catherine Kwon, Carolyn R Bertozzi, Michael J Ferracane, Mark A Lemmon, Rommie E Amaro, Stacy A Malaker. Nature communications. 2023 October;14:6169. [Full Text Article]
[PubMed:37794035]
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