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TIEG / KLF10

Kruppel-like factor 10

TIEG / KLF10 is a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.

Gene Name:	Kruppel-like factor 10
Synonyms:	KLF10, EGR-alpha, Kruppel-like factor 10, TIEG-1, TIEG1, EGRA, Krueppel-like factor 10, TIEG
Target Sequences:	NM_005655 NP_005646.1 Q13118

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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