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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TICAM2 / TRAM

toll-like receptor adaptor molecule 2

Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. May also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB; however, reports are controversial. Involved in IL-18 signaling and is proposed to function as a sorting adaptor for MYD88 in IL-18 signaling during adaptive immune response.Isoform 2: Proposed to inhibit LPS-TLR4 signaling at the late endosome by interaction with isoform 1 thereby disrupting the association of isoform 1 with TICAM1. May be involved in TLR4 degradation in late endosomes.

Gene Name: toll-like receptor adaptor molecule 2
Synonyms: TICAM2, Cytoplasmic adaptor, TRIF-related adapter molecule, TIRAP3, TRIF-related adaptor molecule, TICAM-2, TIRP, TRAM
Target Sequences: NM_021649 NP_067681.1 Q86XR7

Filtered By: None
Target
TICAM2 / TRAM (52)
Reactivity
Human (42)
Mouse (18)
Rat (9)
Bovine (5)
Chicken (4)
Chimpanzee (3)
Dog (4)
Guinea pig (4)
Horse (4)
Monkey (6)
Opossum (1)
Orangutan (3)
Pig (4)
Rabbit (4)
Xenopus (4)
Zebrafish (4)
Application
IHC (16)
IHC-P (4)
WB (49)
ELISA (11)
ICC (3)
IF (2)
Host
rabbit (51)
goat (1)
Isotype
IgG (37)
Clonality
polyclonal pc (52)
Format
AP Conjugated (1)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (7)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (7)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (22)
Epitope
aa20-196 (10)
aa22-205 (10)
aa12-41 (8)
C-Terminus (5)
N-Terminus (4)
aa168-217 (4)
aa2-29 (2)
aa1-232 (1)
aa1-235 (1)
aa150-200 (1)
aa87-103 (1)
Publications
No (52)
Showing 1-25 of 52 results

TICAM2 / TRAM Antibody (C-Terminus) IHC-plus™ LS-B713
Rabbit Polyclonal to Human TICAM2 / TRAM
Human
IHC IHC-P WB
Unconjugated
50µg  $425.00
Anti-TICAM2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot of TIRP in PC-3 cell lysate with TIRP antibody at 1 g/ml.
Anti-TICAM2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot of TIRP in PC-3 cell lysate with TIRP antibody at 1 g/ml.

TICAM2 / TRAM Antibody (C-Terminus) LS-C363
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Mouse, Rat, Human
ELISA IF IHC WB
Unconjugated
100µg 1mg/ml  $365.00
IHC of mouse kidney using TIRP antibody at 2 ug/ml.
Immunofluorescence of TIRP in Mouse Kidney cells with TIRP antibody at 20 ug/ml.
IHC of mouse kidney using TIRP antibody at 2 ug/ml.
Immunofluorescence of TIRP in Mouse Kidney cells with TIRP antibody at 20 ug/ml.

TICAM2 / TRAM Antibody (C-Terminus) LS-C344
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
ICC IF WB
Unconjugated
100µg 1mg/ml  $365.00
Immunocytochemistry of TIRP in Raji cells with TIRP antibody at 10 ug/ml.
Immunofluorescence of TIRP in Raji cells with TIRP antibody at 10 ug/ml.
Immunocytochemistry of TIRP in Raji cells with TIRP antibody at 10 ug/ml.
Immunofluorescence of TIRP in Raji cells with TIRP antibody at 10 ug/ml.

TICAM2 / TRAM Antibody LS-C401763
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using TICAM2 Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human tonsil using TICAM2 Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human thyroid cancer using TICAM2 Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human tonsil using TICAM2 Polyclonal Antibody at dilution of 1:60.

TICAM2 / TRAM Antibody (aa87-103) LS-C148195
Rabbit Polyclonal to Human TICAM2 / TRAM
Human, Monkey
IHC IHC-P WB
Unconjugated
100µg  $335.00

TICAM2 / TRAM Antibody (aa1-235) LS-C378004
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
ELISA IHC IHC-P
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human testis cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human colon cancer cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human testis cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human colon cancer cancer using antibody at 1:100 dilution.

TICAM2 / TRAM Antibody (aa150-200) LS-C148635
Rabbit Polyclonal to Human TICAM2 / TRAM
Mouse, Bovine, Rat, Opossum, Human, Monkey
IHC IHC-P WB
Unconjugated
100µg  $335.00
IHC of TAG/TIRAP3b in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top left) and Polyclonal Antibody to TAG/TIRAP3b (bottom left, right) at 5 ug/ml.
Western blot of TAG/TIRAP3b in K562 cell lysate in the 1) absence and 2) presence of immunizing peptide using Polyclonal Antibody to TAG/TIRAP3b at 3 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.
IHC of TAG/TIRAP3b in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top left) and Polyclonal Antibody to TAG/TIRAP3b (bottom left, right) at 5 ug/ml.
Western blot of TAG/TIRAP3b in K562 cell lysate in the 1) absence and 2) presence of immunizing peptide using Polyclonal Antibody to TAG/TIRAP3b at 3 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.

TICAM2 / TRAM Antibody (C-Terminus) LS-C10828
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Mouse, Rat, Human
IHC WB
Unconjugated
100µg  $515.00

TICAM2 / TRAM Antibody (aa22-205) LS-C296710
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TICAM2 / TRAM Antibody (aa22-205, HRP) LS-C713802
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $345.00; 1ml  $680.00; 10ml  $2,730.00
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TICAM2 / TRAM Antibody (aa22-205, Biotin) LS-C688893
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $575.00; 10ml  $2,310.00
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TICAM2 / TRAM Antibody (aa22-205, FITC) LS-C695924
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
IHC WB
FITC Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TICAM2 / TRAM Antibody (aa22-205, APC, Cy7) LS-C736784
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
IHC WB
APC, Cy7 Conjugated
20µl  $285.00; 100µl  $455.00; 200µl  $635.00; 1ml  $1,575.00; 10ml  $6,300.00
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TICAM2 / TRAM Antibody (aa22-205, Cy3) LS-C704791
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $355.00; 200µl  $445.00; 1ml  $1,050.00; 10ml  $4,200.00
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TICAM2 / TRAM Antibody (aa22-205, PE) LS-C727875
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
IHC WB
PE Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TICAM2 / TRAM Antibody (aa22-205, APC) LS-C718985
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
IHC WB
APC Conjugated
20µl  $225.00; 100µl  $305.00; 200µl  $375.00; 1ml  $785.00; 10ml  $7,470.00
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TICAM2 / TRAM.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TICAM2 / TRAM Antibody LS-C405066
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human brain using TICAM2 Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human brain using TICAM2 Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human brain using TICAM2 Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human brain using TICAM2 Polyclonal Antibody at dilution of 1:60.

TICAM2 / TRAM Antibody (aa20-196, Biotin) LS-C424378
Rabbit Polyclonal (IgG) to Mouse TICAM2 / TRAM
Mouse
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $375.00

TICAM2 / TRAM Antibody (aa20-196, FITC) LS-C424379
Rabbit Polyclonal (IgG) to Mouse TICAM2 / TRAM
Mouse
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $395.00

TICAM2 / TRAM Antibody (aa12-41) LS-C325727
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
ELISA WB
Unconjugated
200µl  $530.00

TICAM2 / TRAM Antibody (aa12-41, Biotin) LS-C271479
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

TICAM2 / TRAM Antibody (aa12-41, FITC) LS-C271480
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
ELISA WB
FITC Conjugated
200µl  $680.00

TICAM2 / TRAM Antibody (aa12-41, APC) LS-C271477
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
ELISA WB
APC Conjugated
200µl  $680.00

TICAM2 / TRAM Antibody (aa12-41, AP) LS-C271478
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
ELISA WB
AP Conjugated
200µl  $680.00

TICAM2 / TRAM Antibody (aa12-41, Azide-free, HRP) LS-C271481
Rabbit Polyclonal (IgG) to Human TICAM2 / TRAM
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00
Showing 1-25 of 52 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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