TIAM2

T-cell lymphoma invasion and metastasis 2

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane (By similarity). Activates specifically RAC1, but not CDC42 and RHOA.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

TIAM2 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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TIAM2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121742

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.6 kDa

Price:

100 µg/$710

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Human TIAM2 Protein (Recombinant GST) (Full Length) - LS-G33129

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

97.2 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TIAM2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89756

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.6 kDa

Price:

20 µg/$215

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Human TIAM2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71433

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.6 kDa

Price:

20 µg/$1,107

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Human TIAM2 Protein (Recombinant GST, N-terminus) (aa527-624) - LS-G62160

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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