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TH / Tyrosine Hydroxylase

tyrosine hydroxylase

Tyrosine hydroxylase in involved in the conversion of phenylalanine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines and as such has a key role in the physiology of adrenergic neurons. TH is encoded by four distinct mRNAs produced by alternative splicing of a single primary transcript. Expression of the mRNAs varies in different parts of the nervous system. Defects in TH are the cause of autosomal recessive Segawa syndrome.

Gene Name: tyrosine hydroxylase
Family/Subfamily: Monooxygenase
Synonyms: TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase
Target Sequences: NM_000360 NP_000351.2 P07101

Publications (6)

1
Chronic Sleep Disruption Advances the Temporal Progression of Tauopathy in P301S Mutant Mice. Zhu Y, Zhan G, Fenik P, Brandes M, Bell P, Francois N, Shulman K, Veasey S. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2018 November;38:10255-10270. [Full Text Article] [PubMed:30322903] [PMC:PMC6262148] Related Antibodies: LS-C124752.
2
Dorsomedial hypothalamic NPY affects cholecystokinin-induced satiety via modulation of brain stem catecholamine neuronal signaling. de La Serre CB, Kim YJ, Moran TH, Bi S. American journal of physiology. Regulatory, integrative and comparative physiology. 2016 November;311:R930-R939. [Full Text Article] [PubMed:27534875] [PMC:PMC5130582]
3
Single-Cell RNA-seq Reveals Profound Alterations in Mechanosensitive Dorsal Root Ganglion Neurons with Vitamin E Deficiency. Finno CJ, Peterson J, Kang M, Park S, Bordbari MH, Durbin-Johnson B, Settles M, Perez-Flores MC, Lee JH, Yamoah EN. iScience. 2019 November;21:720-735. [Full Text Article] [PubMed:31733517] [PMC:PMC6864320] Related Antibodies: LS-C354112.
4
Targeted ablation of cardiac sympathetic neurons attenuates adverse postinfarction remodelling and left ventricular dysfunction. Liang Xiong, Yu Liu, Mingmin Zhou, Guangji Wang, Dajun Quan, Wei Shuai, Caijie Shen, Bin Kong, Congxin Huang, He Huang. Experimental physiology. 2018 September;103:1221-1229. [Full Text Article] [PubMed:29928790] Related Antibodies: LS-C354110.
5
Ganglionated Plexi Ablation Suppresses Chronic Obstructive Sleep Apnea-Related Atrial Fibrillation by Inhibiting Cardiac Autonomic Hyperactivation. Ling Zhang, Yankai Guo , Jiasuoer Xiaokereti , Guiqiu Cao, Hongliang Li, Huaxin Sun , Kai Li , Xianhui Zhou , Baopeng Tang. Frontiers in physiology. 2021 Apr;12:640295. [Full Text Article] [PubMed:33897452] [PMC:PMC8063039] Related Antibodies: LS-C354110.
6
Histopathological Analysis of Adrenal Glands after Simian Varicella Virus Infection. Christy S Niemeyer, Teresa Mescher, Rocio Griggs, David J Orlicky, Gregory K Wilkerson, Andrew N Bubak, James E Hassell Jr, Brittany Feia, Ravi Mahalingam, Vicki Traina-Dorge, Maria A Nagel. Viruses. 2021 Jun;13:1245. [Full Text Article] [PubMed:34206909] [PMC:PMC8310062] Related Antibodies: LS-B12072.
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ELISA Kits (27)
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TH / Tyrosine Hydroxylase (27)
Human (8)
Mouse (7)
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96-Well Microplate (5)
96-Well Strip Plate (19)
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Cell Culture Supernatants (4)
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TH / Tyrosine Hydroxylase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$798
TH / Tyrosine Hydroxylase ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TH / Tyrosine Hydroxylase ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Dog
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
TH / Tyrosine Hydroxylase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$748
TH / Tyrosine Hydroxylase ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
TH / Tyrosine Hydroxylase ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
TH / Tyrosine Hydroxylase ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
13.72 - 10000 pg/ml
Chemiluminescent
Plasma, Serum, Tissue Homogenates
1 Plate/$911
TH / Tyrosine Hydroxylase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$750
TH / Tyrosine Hydroxylase ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
TH / Tyrosine Hydroxylase ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
TH / Tyrosine Hydroxylase ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
TH / Tyrosine Hydroxylase ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
TH / Tyrosine Hydroxylase ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
TH / Tyrosine Hydroxylase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TH / Tyrosine Hydroxylase ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
TH / Tyrosine Hydroxylase ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
TH / Tyrosine Hydroxylase ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
TH / Tyrosine Hydroxylase ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
TH / Tyrosine Hydroxylase ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
TH / Tyrosine Hydroxylase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$968
TH / Tyrosine Hydroxylase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
TH / Tyrosine Hydroxylase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
TH / Tyrosine Hydroxylase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
TH / Tyrosine Hydroxylase ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,229; 1000 Wells/$1,826
TH / Tyrosine Hydroxylase ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,305; 1000 Wells/$1,952
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).