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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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TGFB1 / TGF Beta 1

transforming growth factor, beta 1

TGFB1 / TGF Beta 1 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.

Gene Name: transforming growth factor, beta 1
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: TGFB1, CED, DPD1, Diaphyseal dysplasia 1, LAP, Latency-associated peptide, TGF Beta, TGFbeta, TGF-beta 1 protein, TGF-beta-1, TGFB
Target Sequences: NM_000660 NP_000651.3 P01137

Publications (3)

1
Blockade of KCa3.1 ameliorates renal fibrosis through the TGF-ß1/Smad pathway in diabetic mice. Huang C, Shen S, Ma Q, Chen J, Gill A, Pollock CA, Chen XM. Diabetes. 2013 62:2923-34. (WB; Zebrafish) [Full Text Article] [PubMed:23656889] [PMC:PMC3717839]
2
Bone regeneration in minipigs by intrafibrillarly-mineralized collagen loaded with autologous periodontal ligament stem cells. Zhang C, Yan B, Cui Z, Cui S, Zhang T, Wang X, Liu D, Yang R, Jiang N, Zhou Y, Liu Y. Scientific reports. 2017 September;7:10519. (Pig) [Full Text Article] [PubMed:28874877] [PMC:PMC5585269] Related Antibodies: LS-C10852.
3
Integrin a?ß5 in vitro inhibition limits pro-fibrotic response in cardiac fibroblasts of spontaneously hypertensive rats. Perrucci GL, Barbagallo VA, Corlianò M, Tosi D, Santoro R, Nigro P, Poggio P, Bulfamante G, Lombardi F, Pompilio G. Journal of translational medicine. 2018 December;16:352. [Full Text Article] [PubMed:30541573] [PMC:PMC6292173]

Viewing 1-25 of 228 items
TGFB1 / TGF Beta 1 Antibody - Anti-TGFB1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Cancer
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg   0.96mg/ml   $485.00
TGFB1 / TGF Beta 1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
Fast Shipping
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
IHC-P
Unconjugated
100µg   100µl   1mg/ml   $425.00
TGFB1 / TGF Beta 1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
TGFB1 / TGF Beta 1 Antibody - Anti-TGFB1 / TGF Beta 1 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Mouse Monoclonal (IgG1,k) to Human TGFB1 / TGF Beta 1
Human
ELISA, IHC, IHC-P, Neut, WB
Unconjugated
50µg   1mg/ml   $425.00
TGFB1 / TGF Beta 1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl   $425.00
TGFB1 / TGF Beta 1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human
ELISA, IHC, IHC-P
Unconjugated
50µg   $425.00
TGFB1 / TGF Beta 1 Antibody - Immunohistochemical analysis of TGF beta 1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Mouse, Dog, Sheep, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100µl   1mg/ml   $245.00
Select
Goat Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human
ELISA, Flo, ICC, IHC, Neut, WB
Unconjugated
100µg   $245.00
TGFB1 / TGF Beta 1 Antibody - TGFB1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human breast carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
Rabbit Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
TGFB1 / TGF Beta 1 Antibody
Select
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Mouse, Rat, Human
ELISA, IHC
Unconjugated
100µl   $275.00
TGFB1 / TGF Beta 1 Antibody - Mouse Lymph node cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 8%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Mouse TGFB1 / TGF Beta 1
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $335.00
Select
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human
Flo
PE Conjugated
100tst   $695.00
TGFB1 / TGF Beta 1 Antibody - Western Blot; Sample: Recombinant TGFb1, Human.
Select
Rabbit Polyclonal to Human TGFB1 / TGF Beta 1
Human
WB
Biotin Conjugated
100µl   0.5mg/ml   $235.00; 200µl   0.5mg/ml   $265.00; 1ml   0.5mg/ml   $415.00
TGFB1 / TGF Beta 1 Antibody - Anti-Human TGF-ß1 Western Blot Unreduced
Select
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Mouse, Human, Monkey
WB
Unconjugated
500µg   $255.00
Select
Chicken Polyclonal (IgY) to Human TGFB1 / TGF Beta 1
Mouse, Human
ELISA, WB
Biotin Conjugated
50µg   $845.00
Select
(1) Publication(s)
Rabbit Polyclonal (IgG) to Pig TGFB1 / TGF Beta 1
Mouse, Rat, Pig, Human
IHC, WB
Unconjugated
250µg   $455.00
TGFB1 / TGF Beta 1 Antibody - Western blot using TGF beta1 mouse monoclonal antibody against truncated TGF beta1 recombinant protein.
Select
Mouse Monoclonal [clone 4F9C10] (IgG2a) to Human TGFB1 / TGF Beta 1
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µl   $275.00
Select
Mouse Monoclonal (IgG1,k) to Human TGFB1 / TGF Beta 1
Human
ELISA, WB
Unconjugated
100µg   $345.00
Select
Rabbit Polyclonal to Pig TGFB1 / TGF Beta 1
Mouse, Rat, Pig
IHC, WB
Unconjugated
250µg   $455.00
Select
Goat Polyclonal (IgG) to Human TGFB1 / TGF Beta 1
Human
ELISA, Neut
Unconjugated
100µg   $375.00; 500µg   $695.00
Select
Mouse Monoclonal [clone 16TFB] (IgG1,k) to Human TGFB1 / TGF Beta 1
Human
ELISA, SwELISA
Biotin Conjugated
50µg   0.5mg/ml   $235.00; 500µg   0.5mg/ml   $365.00
Select
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Human
Flo
PE Conjugated
100tst   $695.00
Select
Mouse Monoclonal (IgG1) to Human TGFB1 / TGF Beta 1
Rabbit, Mouse, Sheep, Rat, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
100µl   1mg/ml   $800.00
TGFB1 / TGF Beta 1 Antibody - IHC of paraffin-embedded lung cancer tissues using TGFb1 mouse monoclonal antibody with DAB staining.
Select
Mouse Monoclonal [clone 7F6] (IgG1) to Human TGFB1 / TGF Beta 1
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100µg   1mg/ml   $365.00
TGFB1 / TGF Beta 1 Antibody - Western blot of recombinant TGFB1 / TGF Beta 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal (IgG) to Human TGFB1 / TGF Beta 1
Rat, Human
WB
Unconjugated
20µl   1mg/ml   $195.00; 100µl   1mg/ml   $245.00; 200µl   1mg/ml   $275.00; 1ml   1mg/ml   $455.00

Viewing 1-25 of 228 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).