Products
Services
Research Areas
COVID-19
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

TGFB1 / TGF Beta 1

transforming growth factor, beta 1

TGFB1 / TGF Beta 1 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.

Gene Name: transforming growth factor, beta 1
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: TGFB1, CED, DPD1, Diaphyseal dysplasia 1, LAP, Latency-associated peptide, TGF Beta, TGFbeta, TGF-beta 1 protein, TGF-beta-1, TGFB
Target Sequences: NM_000660 NP_000651.3 P01137

Publications (3)

1
Blockade of KCa3.1 ameliorates renal fibrosis through the TGF-ß1/Smad pathway in diabetic mice. Huang C, Shen S, Ma Q, Chen J, Gill A, Pollock CA, Chen XM. Diabetes. 2013 62:2923-34. (WB; Zebrafish) [Full Text Article] [PubMed:23656889] [PMC:PMC3717839]
2
Bone regeneration in minipigs by intrafibrillarly-mineralized collagen loaded with autologous periodontal ligament stem cells. Zhang C, Yan B, Cui Z, Cui S, Zhang T, Wang X, Liu D, Yang R, Jiang N, Zhou Y, Liu Y. Scientific reports. 2017 September;7:10519. (Pig) [Full Text Article] [PubMed:28874877] [PMC:PMC5585269] Related Antibodies: LS-C10852.
3
Integrin a?ß5 in vitro inhibition limits pro-fibrotic response in cardiac fibroblasts of spontaneously hypertensive rats. Perrucci GL, Barbagallo VA, Corlianò M, Tosi D, Santoro R, Nigro P, Poggio P, Bulfamante G, Lombardi F, Pompilio G. Journal of translational medicine. 2018 December;16:352. [Full Text Article] [PubMed:30541573] [PMC:PMC6292173]

☰ Filters
Antibodies (225)
Primary (225)
TGFB1 / TGF Beta 1 (225)
Human (125)
Mouse (61)
Rat (51)
Bovine (21)
Chicken (12)
Cow (8)
Cynomolgus (2)
Dog (14)
Gibbon (3)
Guinea pig (12)
Horse (7)
Monkey (5)
Pig (16)
Rabbit (17)
Rainbow trout (4)
Sheep (18)
IHC (45)
IHC-P (15)
WB (172)
Flo (19)
ELISA (85)
Func (1)
ICC (8)
IF (16)
IP (2)
Neut (10)
Peptide-ELISA (1)
rabbit (146)
mouse (62)
goat (8)
chicken (1)
guinea pig (8)
Product Group
IHCPlus (4)
PathPlus Cancer (2)
IgG (75)
IgG1 (21)
IgG1,k (14)
IgG2a (8)
IgY (1)
monoclonal mc (63)
polyclonal pc (162)
016 (1)
10E5 (1)
1B4G5B4 (1)
33 (1)
3D9 (1)
3F12 (1)
4F9C10 (1)
5D2 (1)
7F6 (2)
8 (1)
M66 (1)
OTI1E12 (2)
OTI2B5 (2)
OTI3B6 (2)
AP Conjugated (4)
APC (11)
APC Conjugated (17)
Biotin Conjugated (25)
Carrier-free (3)
CF Conjugated (1)
Cy3 Conjugated (11)
Cy7 Conjugated (11)
FITC Conjugated (24)
HRP Conjugated (23)
PE Conjugated (17)
Preservative Free (5)
Unconjugated (92)
aa279-390 (81)
aa260-373 (12)
aa22-50 (8)
aa151-200 (4)
aa30-390 (2)
310-390 aa, C-terminal (1)
Amino Acid: 62-195 (1)
C-Terminus (1)
Tyr369 (1)
aa 281-390 (1)
aa1-111 (1)
aa280-391 (1)
aa286-293 (1)
aa30-278 (1)
No (224)
Yes (1)
TGFB1 / TGF Beta 1 Antibody - Anti-TGFB1 / TGF Beta 1 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
TGFB1 / TGF Beta 1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, Neut, WB
Unconjugated
50 µg/$425
TGFB1 / TGF Beta 1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
TGFB1 / TGF Beta 1 Rabbit anti-Human Polyclonal (310-390 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$425
TGFB1 / TGF Beta 1 Antibody - Anti-TGFB1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Cancer
TGFB1 / TGF Beta 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$485
TGFB1 / TGF Beta 1 Antibody - Immunohistochemical analysis of TGF beta 1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
TGFB1 / TGF Beta 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$245
Select
TGFB1 / TGF Beta 1 Goat anti-Human Polyclonal Antibody
Human
ELISA, Flo, ICC, IHC, Neut, WB
Unconjugated
100 µg/$245
TGFB1 / TGF Beta 1 Antibody - TGFB1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human breast carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
TGFB1 / TGF Beta 1 Rabbit anti-Human Polyclonal (aa22-50) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$325
TGFB1 / TGF Beta 1 Antibody
Select
TGFB1 / TGF Beta 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
100 µl/$265
TGFB1 / TGF Beta 1 Antibody - Mouse Lymph node cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 8%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TGFB1 / TGF Beta 1 Rabbit anti-Mouse Polyclonal (aa151-200) Antibody
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Human, Monkey
WB
Unconjugated
100 µl/$335
Select
TGFB1 / TGF Beta 1 Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$695
TGFB1 / TGF Beta 1 Antibody - Western Blot; Sample: Recombinant TGFb1, Human.
Select
TGFB1 / TGF Beta 1 Rabbit anti-Human Polyclonal (aa279-390) (Biotin) Antibody
Human
WB
Biotin Conjugated
200 µl/$265; 500 µl/$365; 1 ml/$415
Select
TGFB1 / TGF Beta 1 Rabbit anti-Pig Polyclonal Antibody
Mouse, Rat, Pig, Human
IHC, WB
Unconjugated
250 µg/$455
TGFB1 / TGF Beta 1 Antibody - Anti-Human TGF-ß1 Western Blot Unreduced
Select
TGFB1 / TGF Beta 1 Mouse anti-Human Monoclonal Antibody
Mouse, Human, Monkey
WB
Unconjugated
500 µg/$255
Select
TGFB1 / TGF Beta 1 Chicken anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
50 µg/$845
Select
TGFB1 / TGF Beta 1 Mouse anti-Human Monoclonal (Biotin) Antibody
Rabbit, Mouse, Sheep, Rat, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
100 µl/$800
TGFB1 / TGF Beta 1 Antibody - Western blot using TGF beta1 mouse monoclonal antibody against truncated TGF beta1 recombinant protein.
Select
TGFB1 / TGF Beta 1 Mouse anti-Human Monoclonal (4F9C10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µl/$275
Select
TGFB1 / TGF Beta 1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$345
Select
TGFB1 / TGF Beta 1 Rabbit anti-Pig Polyclonal (aa280-391) Antibody
Mouse, Rat, Pig
IHC, WB
Unconjugated
250 µg/$455
TGFB1 / TGF Beta 1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
TGFB1 / TGF Beta 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$425
Select
TGFB1 / TGF Beta 1 Goat anti-Human Polyclonal Antibody
Human
ELISA, Neut
Unconjugated
100 µg/$375; 500 µg/$695
Select
TGFB1 / TGF Beta 1 Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$695
TGFB1 / TGF Beta 1 Antibody - Western Blot; Sample: Recombinant TGFb1, Gallus.
Select
TGFB1 / TGF Beta 1 Rabbit anti-Chicken Polyclonal (aa260-373) Antibody
Chicken
WB
Unconjugated
100 µl/$255; 200 µl/$295; 500 µl/$435; 1 ml/$515
TGFB1 / TGF Beta 1 Antibody - Anti-TGFB1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TGFB1.
Select
TGFB1 / TGF Beta 1 Mouse anti-Human Monoclonal (OTI1E12) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$345
TGFB1 / TGF Beta 1 Antibody - IHC of paraffin-embedded lung cancer tissues using TGFb1 mouse monoclonal antibody with DAB staining.
Select
TGFB1 / TGF Beta 1 Mouse anti-Human Monoclonal (7F6) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$365
TGFB1 / TGF Beta 1 Antibody - Western blot of recombinant TGFB1 / TGF Beta 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TGFB1 / TGF Beta 1 Mouse anti-Human Monoclonal (aa279-390) Antibody
Rat, Human
WB
Unconjugated
100 µl/$245; 200 µl/$275; 500 µl/$395; 1 ml/$455
TGFB1 / TGF Beta 1 Antibody - Western analysis of TGF-B1 in RAW264.7 cells.
Select
TGFB1 / TGF Beta 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Pig, Human
WB
Unconjugated
30 µg/$265; 100 µg/$485
Viewing 1-25 of 225 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).