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TGFA / TGF Alpha is a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
|Gene Name:||transforming growth factor, alpha|
|Family/Subfamily:||TGF beta , not assigned-TGF beta|
|Synonyms:||TGFA, Etgf, TFGA, TGF Alpha, Tgf type 1, TGF-alpha, Egf-like tgf|
|Target Sequences:||NM_003236 NP_003227.1 P01135|
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