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TFPI / LACI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

TFPI / LACI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.

Gene Name: tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Synonyms: TFPI, Anti-convertin, Extrinsic pathway inhibitor, EPI, LACI, TFI, TFPI1
Target Sequences: NM_006287 NP_006278.1 P10646

☰ Filters
Products
Proteins (20)
Over-Expression Lysate (4)
Recombinant (16)
TFPI / LACI (20)
No (20)
10His, N-terminus (1)
GST (2)
GST, N-terminus (1)
His (6)
His,C-terminus (1)
His-GST (3)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (11)
Mouse (2)
Rabbit (4)
Rat (1)
293T Cells (2)
Baculovirus (1)
E. coli (9)
HEK 293 Cells (4)
Human Cells (1)
Wheat Germ Extract (2)
Yeast (1)
Purified (5)
Low endotoxin level (2)
TFPI / LACI Protein - Recombinant Tissue Factor Pathway Inhibitor By SDS-PAGE
Select
E. coli
His-GST
59.2 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
TFPI / LACI Protein - Recombinant Tissue Factor Pathway Inhibitor By SDS-PAGE
Select
E. coli
His
32 kDa
10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646
TFPI / LACI Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Baculovirus
10His, N-terminus
34.3 kDa
100 µg/$1,164; 20 µg/$475; 1 mg/$2,187
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.6 kDa
50 µg/$710; 500 µg/$2,999
TFPI / LACI Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TFPI / LACI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
28.65 kDa
100 µg/$494
TFPI / LACI Protein - 12.5% SDS-PAGE of human TFPI stained with Coomassie Blue
Select
Wheat Germ Extract
GST
53.35 kDa
10 µg/$479; 25 µg/$670
TFPI / LACI Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
E. coli
His
35.9 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
Select
Yeast
His
33.8 kD
100 µg/$679; 20 µg/$429; 1 mg/$1,973
Select
E. coli
GST
56.3 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
TFPI / LACI Protein - Purified recombinant protein TFPI was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
25.5 kDa
20 µg/$1,107
Select
293T Cells
Myc-DDK (Flag)
28.65 kDa
20 µg/$150
TFPI / LACI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
35.02 kDa
20 µg/$150
TFPI / LACI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
35.02 kDa
100 µg/$494
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
31 kDa
50 µg/$854
TFPI / LACI Protein - Recombinant Tissue Factor Pathway Inhibitor By SDS-PAGE
Select
E. coli
His-GST
63.9 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
TFPI / LACI Protein - Recombinant Tissue Factor Pathway Inhibitor By SDS-PAGE
Select
E. coli
His-GST
57.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
TFPI / LACI Protein - Recombinant Tissue Factor Pathway Inhibitor By SDS-PAGE
Select
E. coli
His-T7
35.5 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
TFPI / LACI Protein - Recombinant Tissue Factor Pathway Inhibitor By SDS-PAGE
Select
E. coli
His
22.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Viewing 1-20 of 20 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).