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Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.
Gene Name: | transcription factor CP2 |
Synonyms: | TFCP2, CP2, LSF1D, LSF, LBP-1C, SAA3 enhancer factor, SEF, TFCP2C, Transcription factor CP2, LBP1C, Transcription factor LSF |
Target Sequences: | NM_005653 NP_005644.2 Q12800 |
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