TFAP2A / AP-2

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. Caution: AP-2B refers to both an alternatively spliced form of AP-2 and to the related transcription factor AP-2 beta.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

TFAP2A / AP-2 (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human TFAP2A / AP-2 Protein (Recombinant GST) (Full Length) - LS-G30672

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

74.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TFAP2A / AP-2 Protein (Recombinant GST, N-terminus) (aa99-205) - LS-G60323

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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TFAP2A / AP-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119504

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.3 kDa

Price:

100 µg/$710

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TFAP2A / AP-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120839

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47 kDa

Price:

100 µg/$494

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Human TFAP2A / AP-2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67136

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47 kDa

Price:

20 µg/$1,107

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Human TFAP2A / AP-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79210

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.3 kDa

Price:

20 µg/$215

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Human TFAP2A / AP-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79211

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47 kDa

Price:

20 µg/$150

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