TEX14

testis expressed 14

Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

TEX14 (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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TEX14 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109302

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

162.5 kDa

Price:

100 µg/$710

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Human TEX14 Protein (Recombinant GST, N-terminus) (aa1392-1491) - LS-G62829

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TEX14 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85375

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

162.5 kDa

Price:

20 µg/$215

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