TEF

thyrotrophic embryonic factor

TEF is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP); VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

TEF (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human TEF Protein (Recombinant GST, N-terminus) (aa214-303) - LS-G60318

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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TEF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117486

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.1 kDa

Price:

100 µg/$494

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Human TEF Protein (Recombinant GST) (Full Length) - LS-G30666

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

59.6 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TEF Protein (Recombinant His) - LS-G2390

Source:

E. coli

Tag:

His

Price:

20 µg/$348; 100 µg/$511; 10 µg/$286; 50 µg/$392; 250 µg/$872; 500 µg/$1,355

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Human TEF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79189

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.1 kDa

Price:

20 µg/$150

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