TCF3 / E2A

transcription factor 3

TCF3 / E2A is a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

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ELISA Kits (4)

Type

Competitive EIA (2)

Custom (2)

Target

TCF3 / E2A (4)

Reactivity

Human (2)

Mouse (1)

Rat (1)

Format

96-Well Strip Plate (4)

Publications

No (4)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (1)

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Rat TCF3 / E2A (Custom ELISA) ELISA Kit - LS-F17572

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Mouse TCF3 / E2A (Custom ELISA) ELISA Kit - LS-F17573

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human TCF3 / E2A (Competitive EIA) ELISA Kit - LS-F13464

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human TCF3 / E2A (Competitive EIA) ELISA Kit - LS-F39365

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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