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Unfortunately, the antibody LS-C178350 is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



TCAB1 / WDR79 Antibodies

WD repeat containing, antisense to TP53

Gene Name: WD repeat containing, antisense to TP53
Synonyms: WRAP53 Antibody, DKCB3 Antibody, WDR79 Antibody, TCAB1 Antibody, WD repeat domain 79 Antibody, WD40 protein Wrap53 Antibody
Target Sequences: NM_018081 NP_060551.2 Q9BUR4
 TCAB1 / WDR79 Feature Table

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Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
TCAB1 / WDR79 Rabbit IgG Polyclonal Unconjugated Human IHC-P, IF, WB, IP aa1-50 No Primary
Anti-TCAB1 / WDR79 Antibody (aa1-50) LS-C288235
IHC Image
Rabbit Polyclonal (IgG) to Human TCAB1 / WDR79
Human
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
TCAB1 / WDR79 Rabbit IgG Polyclonal Unconjugated Human IHC-P, IF aa1-50 No Primary
Anti-TCAB1 / WDR79 Antibody (aa1-50) LS-C286747
IHC Image
Rabbit Polyclonal (IgG) to Human TCAB1 / WDR79
Human
IHC - Paraffin, Immunofluorescence
Unconjugated

TCAB1 / WDR79 Feature Table


Feature Type Location Details
Function 1 - 548 Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post- transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.
ptm 1 - 548 Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity 1 - 548 Contains 6 WD repeats.
Subcellular Location 1 - 548 Nucleus, Cajal body. Cytoplasm.
Subunit 1 - 548 Component of the telomerase holoenzyme complex at least composed of TERT, DKC1, WRAP53/TCAB1, NOP10, NHP2, GAR1, TEP1, EST1A, POT1 and a telomerase RNA template component (TERC).
Tissue Specificity 1 - 548 Expressed in all tissues and cell lines examined.
arrayexpress 1 - 548 Q9BUR4
bgee 1 - 548 Q9BUR4
cleanex 1 - 548 HS_WDR79
ctd 1 - 548 55135
doi 1 - 548 10
eggnog 1 - 548 prNOG11684
embl 1 - 548 AK001247
embl 1 - 548 AK056669
embl 1 - 548 AY766322
embl 1 - 548 BC002336
embl 1 - 548 DQ431240
embl 1 - 548 DQ431241
ensembl 1 - 548 ENST00000316024
ensembl 1 - 548 ENST00000396463
ensembl 1 - 548 ENST00000431639
ensembl 1 - 548 ENST00000457584
gene3d 1 - 548 G3DSA:2.130.10.10
genecards 1 - 548 GC17P007589
geneid 1 - 548 55135
genevestigator 1 - 548 Q9BUR4
germonline 1 - 548 ENSG00000141499
go 1 - 548 GO:0003723
go 1 - 548 GO:0005515
go 1 - 548 GO:0005697
go 1 - 548 GO:0005737
go 1 - 548 GO:0015030
go 1 - 548 GO:0032203
go 1 - 548 GO:0051973
h-invdb 1 - 548 HIX0013509
hgnc 1 - 548 HGNC:25522
hogenom 1 - 548 HBG318530
hovergen 1 - 548 HBG098609
inparanoid 1 - 548 Q9BUR4
interpro 1 - 548 IPR001680
interpro 1 - 548 IPR011046
interpro 1 - 548 IPR015943
interpro 1 - 548 IPR017986
interpro 1 - 548 IPR019781
interpro 1 - 548 IPR019782
ipi 1 - 548 IPI00306087
kegg 1 - 548 hsa:55135
mim 1 - 548 612661
nextbio 1 - 548 58818
oma 1 - 548 YAEMVPV
orthodb 1 - 548 EOG9TQPVS
peptideatlas 1 - 548 Q9BUR4
pfam 1 - 548 PF00400
pharmgkb 1 - 548 PA142670583
phosphosite 1 - 548 Q9BUR4
phylomedb 1 - 548 Q9BUR4
pride 1 - 548 Q9BUR4
prosite 1 - 548 PS00678
prosite 1 - 548 PS50082
prosite 1 - 548 PS50294
proteinmodelportal 1 - 548 Q9BUR4
pubmed 1 - 548 14702039
pubmed 1 - 548 15489334
pubmed 1 - 548 17081983
pubmed 1 - 548 17525332
pubmed 1 - 548 17693683
pubmed 1 - 548 18220336
pubmed 1 - 548 18669648
pubmed 1 - 548 19179534
pubmed 1 - 548 19250907
pubmed 1 - 548 19690332
refseq 1 - 548 NP_001137462.1
refseq 1 - 548 NP_001137463.1
refseq 1 - 548 NP_001137464.1
refseq 1 - 548 NP_060551.2
smart 1 - 548 SM00320
smr 1 - 548 Q9BUR4
string 1 - 548 Q9BUR4
supfam 1 - 548 SSF50978
ucsc 1 - 548 uc002gip.1
unigene 1 - 548 Hs.437460
chain 1 - 548 Telomerase Cajal body protein 1 /FTId=PRO_0000242696.
compbias 8 - 57 Pro-rich
conflict 21 - 21 A -> V (in Ref. 2; BAA91579)
conflict 497 - 497 E -> G (in Ref. 2; BAG51781)
conflict 526 - 526 S -> G (in Ref. 2; BAG51781)
Modification 26 - 26 Phosphoserine
Modification 30 - 30 Phosphoserine
Modification 54 - 54 Phosphoserine
Modification 64 - 64 Phosphoserine
Modification 85 - 85 Phosphoserine
Modification 90 - 90 Phosphoserine
Modification 112 - 112 Phosphoserine
Modification 114 - 114 Phosphoserine
Modification 489 - 489 Phosphothreonine
Modification 491 - 491 Phosphoserine
repeat 167 - 206 WD 1
repeat 222 - 267 WD 2
repeat 272 - 313 WD 3
repeat 323 - 364 WD 4
repeat 365 - 405 WD 5
repeat 411 - 450 WD 6
variant 11 - 11 P -> S (in dbSNP:rs17880282) /FTId=VAR_026865.
variant 68 - 68 R -> G (in dbSNP:rs2287499) /FTId=VAR_026866.
variant 136 - 136 P -> R (in dbSNP:rs34067256) /FTId=VAR_057618.
variant 187 - 187 N -> T (in dbSNP:rs35762939) /FTId=VAR_057619.
variant 494 - 494 E -> Q (in dbSNP:rs35123152) /FTId=VAR_057620.
variant 522 - 522 A -> G (in dbSNP:rs7640) /FTId=VAR_026867.
keyword 1 - 548 Complete proteome
keyword 1 - 548 Cytoplasm
keyword 1 - 548 Nucleus
keyword 1 - 548 Phosphoprotein
keyword 1 - 548 Polymorphism
keyword 1 - 548 Repeat
keyword 1 - 548 RNA-binding
keyword 1 - 548 WD repeat
Molecular Weight 1 - 548 59309
6 hits 1 - 548 PF00400
1 hit 1 - 548 PS50294
2 hits 1 - 548 PS50082
false_neg 1 - 548 PS00678

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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