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TBP / GTF2D

TATA box binding protein

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: TATA box binding protein
Synonyms: TBP, GTF2D1, HDL4, TATA box binding protein, TATA-binding factor, TATA-box factor, TFIID, TATA sequence-binding protein, SCA17, TATA-box-binding protein, GTF2D, TF2D
Target Sequences: NM_003194 NP_003185.1 P20226

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ELISA Kits (12)
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TBP / GTF2D (12)
Human (3)
Mouse (2)
Rat (1)
Chicken (2)
Monkey (1)
Porcine (1)
Rabbit (1)
96-Well Strip Plate (12)
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Plasma (4)
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Tissue Homogenates (1)
TBP / GTF2D ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TBP / GTF2D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
TBP / GTF2D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
TBP / GTF2D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
TBP / GTF2D ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
TBP / GTF2D ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
TBP / GTF2D ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
TBP / GTF2D ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
TBP / GTF2D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
TBP / GTF2D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
TBP / GTF2D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
TBP / GTF2D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).