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F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
Gene Name: | transducin (beta)-like 1 X-linked receptor 1 |
Synonyms: | TBL1XR1, DC42, IRA1, TBL1-related protein 1, TBLR1, C21 |
Target Sequences: | NM_024665 NP_078941.2 Q9BZK7 |
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