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TBCC

tubulin folding cofactor C

TBCC encodes the tubulin-specific chaperone c. It is one of 5 tubulin-specific cofactors that assist the multi-subunit cytosolic chaperonin in correctly folding a newly-synthesized beta-tubulin polypeptide into the correct native configuration. Chaperone c interacts directly with beta-tubulin during the cycling process, and thus is believed to either prevent illicit interactions with exposed hydrophobic surfaces on beta-tubulin subunits, or by lifting the target protein over one or more specific kinetic barriers to proper folding.

Gene Name: tubulin folding cofactor C
Synonyms: TBCC, CFC, Cofactor c, Tubulin-specific chaperone C, Tubulin-folding cofactor C, Tubulin folding cofactor C
Target Sequences: NM_003192 NP_003183.1 Q15814

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
TBCC (6)
No (6)
GST (1)
His (2)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
TBCC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
39 kDa
100 µg/$494
TBCC Protein - 12.5% SDS-PAGE of human TBCC stained with Coomassie Blue
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Wheat Germ Extract
GST
63.8 kDa
10 µg/$479; 25 µg/$670
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E. coli
His
43 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
TBCC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
39 kDa
20 µg/$150
TBCC Protein - Purified recombinant protein TBCC was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
39 kDa
20 µg/$1,107
TBCC Protein
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E. coli
His
20 µg/$361; 100 µg/$544; 10 µg/$292; 50 µg/$411; 250 µg/$954; 500 µg/$1,447
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).