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Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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TAX1BP1
Tax1 (human T-cell leukemia virus type I) binding protein 1
TAX1BP1 is a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | Tax1 (human T-cell leukemia virus type I) binding protein 1 |
| Synonyms: | TAX1BP1, CALCOCO3, T6BP, Tax1-binding protein 1, TRAF6-binding protein, TXBP151 |
| Target Sequences: | NM_006024 NP_006015.4 Q86VP1 |
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