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TAX1BP1

Tax1 (human T-cell leukemia virus type I) binding protein 1

TAX1BP1 is a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Tax1 (human T-cell leukemia virus type I) binding protein 1
Synonyms: TAX1BP1, CALCOCO3, T6BP, Tax1-binding protein 1, TRAF6-binding protein, TXBP151
Target Sequences: NM_006024 NP_006015.4 Q86VP1

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).