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JOSD1

Josephin Domain Containing 1

Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity.

Gene Name: Josephin Domain Containing 1
Synonyms: JOSD1, DJ508I15.2, JSPH1, Josephin-1, KIAA0063, Josephin domain-containing 1, Josephin domain containing 1
Target Sequences: NM_014876 NP_055691.1 Q15040

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).