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JOSD1

Josephin Domain Containing 1

Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity.

Gene Name:	Josephin Domain Containing 1
Synonyms:	JOSD1, DJ508I15.2, JSPH1, Josephin-1, KIAA0063, Josephin domain-containing 1, Josephin domain containing 1
Target Sequences:	NM_014876 NP_055691.1 Q15040

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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